Long-Term Complications of Kidney Transplantation
By:
Sean A. Hebert Division of Immunology and Organ Transplantation, University of Texas Health Science Center at Houston, Houston, Texas

Search for other papers by Sean A. Hebert in
Current site
Google Scholar
PubMed Close
and
Hassan N. Ibrahim Division of Immunology and Organ Transplantation, University of Texas Health Science Center at Houston, Houston, Texas

Search for other papers by Hassan N. Ibrahim in
Current site
Google Scholar
PubMed Close
Volume/Issue:
Volume 23: Issue 5
Published Online:
Dec 2024
Restricted access
Purchase Print On-Demand ASN Members Sign In Here
  • Collapse
  • Expand
Cover Nephrology Self-Assessment Program
Copyright:
Copyright © 2024 by the American Society of Nephrology 2024
Page Count:
12
Article Category:
Research Article
Print Publication Date:
01 Dec 2024
Published Online:
Dec 2024
  • 1.

    Alotaibi NE: Incidence and risk factors of infections following kidney transplantation. J Infect Public Health 17: 102491, 2024 PubMed

  • 2.

    Agrawal A, Ison MG, Danziger-Isakov L: Long-term infectious complications of kidney transplantation. Clin J Am Soc Nephrol 17: 286–295, 2022 PubMed

  • 3.

    Hosseinpour M, Pezeshgi A, Mahdiabadi MZ, Sabzghabaei F, Hajishah H, Mahdavynia S: Prevalence and risk factors of urinary tract infection in kidney recipients: A meta-analysis study. BMC Nephrol 24: 284, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4.

    Chan S, Cheung CY, Stewart A, Chen SC, Kotton CN, Hand J, Cochrane Kidney and Transplant Group, et al.: Interventions for preventing urinary tract infections in kidney transplant recipients. Cochrane Library 2023, 2023

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5.

    Kumar R, Pereira M, Taimur S, True K, Detwiler R, Van Duin D: Duration of antibiotic treatment for acute graft pyelonephritis: What’s the standard of care? Transpl Infect Dis 25: e13996, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6.

    McAteer J, Tamma PD: Diagnosing and managing urinary tract infections in kidney transplant recipients. Infect Dis Clin North Am 38: 361–380, 2024 PubMed

  • 7.

    Lee JR, Bang H, Dadhania D, Hartono C, Aull MJ, Satlin M, et al.: Independent risk factors for urinary tract infection and for subsequent bacteremia or acute cellular rejection. Transplantation 96: 732–738, 2013 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8.

    Goldman JD, Julian K: Urinary tract infections in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant 33: e13507, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9.

    Antonio MEE, Cassandra BGC, Emiliano RJD, Guadalupe OLM, Lilian REA, Teresa TGM, et al.: Treatment of asymptomatic bacteriuria in the first 2 months after kidney transplant: A controlled clinical trial. Transpl Infect Dis 24: e13934, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10.

    Goodfellow M, Thompson ER, Tingle SJ, Wilson C: Early versus late removal of urinary catheter after kidney transplantation. Cochrane Database Syst Rev 7: CD013788, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11.

    Thompson ER, Hosgood SA, Nicholson ML, Wilson CH: Early versus late ureteric stent removal after kidney transplantation. Cochrane Database Syst Rev 1: CD011455, 2018 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12.

    Lee JH, Muthukumar T, Kim J, Aull MJ, Watkins A, Kapur S, et al.: Antibiotic prophylaxis for ureteral stent removal after kidney transplantation. Clin Transplant 33: e13491, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 13.

    Rosado-Canto R, Parra-Avila I, Tejeda-Maldonado J, Kauffman-Ortega C, Rodriguez-Covarrubias FT, Trujeque-Matos M, et al.: Perioperative fosfomycin disodium prophylaxis against urinary tract infection in renal transplant recipients: A randomized clinical trial. Nephrol Dial Transplant 35: 1996–2003, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14.

    Jent P, Berger J, Kuhn A, Trautner BW, Atkinson A, Marschall J: Antibiotics for preventing recurrent urinary tract infection: Systematic review and meta-analysis. Open Forum Infect Dis 9: ofac327, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15.

    Li JM, Cosler LE, Harausz EP, Myers CE, Kufel WD: Methenamine for urinary tract infection prophylaxis: A systematic review. Pharmacotherapy 44: 197–206, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16.

    Hollyer I, Varias F, Ho B, Ison MG: Safety and efficacy of methenamine hippurate for the prevention of recurrent urinary tract infections in adult renal transplant recipients: A single center, retrospective study. Transpl Infect Dis 21: e13063, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 17.

    Bilsen MP, van Uhm JIM, Stalenhoef JE, van Nieuwkoop C, Groenwold RHH, Visser LG, et al.: Intravesical aminoglycoside instillations as prophylaxis for recurrent urinary tract infection: Patient satisfaction, long-term safety and efficacy. Jac Antimicrob Resist 5: dlad040, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 18.

    Imlay H, Wagener MM, Vutien P, Perkins J, Singh N, Limaye AP: Increasing proportion of high-risk cytomegalovirus donor-positive/recipient-negative serostatus in solid organ transplant recipients. Transplantation 107: 988–993, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 19.

    Kumar L, Murray-Krezan C, Singh N, Brennan DC, Rakita RM, Dasgupta S, et al.: A systematic review and meta-analysis of optimized CMV preemptive therapy and antiviral prophylaxis for CMV disease prevention in CMV High-Risk (D+R-) kidney transplant recipients. Transplant Direct 9: e1514, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 20.

    Reischig T, Vlas T, Kacer M, Pivovarcikova K, Lysak D, Nemcova J, et al.: A randomized trial of valganciclovir prophylaxis versus preemptive therapy in kidney transplant recipients. J Am Soc Nephrol 34: 920–934, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 21.

    Raglow Z, Kaul DR: A new antiviral option for cytomegalovirus prevention after kidney transplant. JAMA 330: 27–29, 2023 PubMed

  • 22.

    Limaye AP, Budde K, Humar A, Vincenti F, Kuypers DRJ, Carroll RP, et al.: Letermovir vs valganciclovir for prophylaxis of cytomegalovirus in high-risk kidney transplant recipients. JAMA 330: 33–42, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 23.

    Reischig T, Kacer M, Hes O, Machova J, Nemcova J, Lysak D, et al.: Cytomegalovirus prevention strategies and the risk of BK polyomavirus viremia and nephropathy. Am J Transplant 19: 2457–2467, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 24.

    Adekunle RO, Zhang R, Wang Z, Patzer RE, Mehta AK: Early steps to kidney transplantation among persons with HIV and end‐stage renal disease in ESRD network 6. Transpl Infect Dis 24: e13767, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 25.

    Motter JD, Hussain S, Brown DM, Florman S, Rana MM, Friedman-Moraco R, HOPE in Action Investigators, et al.: Wait time advantage for transplant candidates with HIV who accept kidneys from donors with HIV under the HOPE Act. Transplantation 108: 759–767, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 26.

    Fontana L, Swanson KJ, El-Rifai R, Bregman A, Spong R, Kirchner VA, et al.: Recipient and kidney graft outcomes of deceased donors with human immunodeficiency virus in the United States. Transpl Infect Dis 25: e14093, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 27.

    Durand CM, Martinez N, Neumann K, Benedict RC, Baker AW, Wolfe CR, HOPE in Action Investigators, et al.: Living kidney donors with HIV: Experience and outcomes from a case series by the HOPE in Action Consortium. Lancet Reg Health Am 24: 100553, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 28.

    Blasi M, Stadtler H, Chang J, Hemmersbach-Miller M, Wyatt C, Klotman P, et al.: Detection of donor’s HIV strain in HIV-positive kidney-transplant recipient. N Engl J Med 382: 195–197, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 29.

    Al-Adra D, Al-Qaoud T, Fowler K, Wong G: De novo malignancies after kidney transplantation. Clin J Am Soc Nephrol 17: 434–443, 2022 PubMed

  • 30.

    Ietto G, Gritti M, Pettinato G, Carcano G, Gasperina DD: Tumors after kidney transplantation: A population study. World J Surg Oncol 21: 18, 2023 PubMed

  • 31.

    Knoll GA, Kokolo MB, Mallick R, Beck A, Buenaventura CD, Ducharme R, et al.: Effect of sirolimus on malignancy and survival after kidney transplantation: Systematic review and meta-analysis of individual patient data. BMJ 349: g6679, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 32.

    Chung CL, Nadhan KS, Shaver CM, Ogrich LM, Abdelmalek M, Cusack CA, et al.: Comparison of posttransplant dermatologic diseases by race. JAMA Dermatol 153: 552–558, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 33.

    Wheless L, Anand N, Hanlon A, Chren MM: Differences in skin cancer rates by transplanted organ type and patient age after organ transplant in White patients. JAMA Dermatol 158: 1287–1292, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 34.

    Ali H, Briggs D, Krishnan N: 412.9: Association of skin cancer with the use of azathioprine and mycophenolate mofetil in kidney transplant recipients. Transplantation 106: S406–S406, 2022

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 35.

    Thet Z, Lam AK-Y, Ng S-K, Aung SY, Han T, Ranganathan D, et al.: Comparison of skin cancer risk between renal transplant recipients and patients with glomerular diseases in rural Queensland. Aust J Rural Health 32: 249–262, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 36.

    Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, et al.: A phase 3 randomized trial of nicotinamide for skin-cancer chemoprevention. N Engl J Med 373: 1618–1626, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 37.

    Allen NC, Martin AJ, Snaidr VA, Eggins R, Chong AH, Fernandéz-Peñas P, et al.: Nicotinamide for skin-cancer chemoprevention in transplant recipients. N Engl J Med 388: 804–812, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 38.

    Hadeler EK, Maderal AD: Drug interactions of natural supplements in dermatology: A review. Int J Dermatol 60: 1183–1189, 2021 PubMed

  • 39.

    Attieh RM, Wadei HM, Mao MA, Mao SA, Pungpapong S, Taner CB, et al.: The impact of induction therapy on the risk of posttransplant lymphoproliferative disorder in adult kidney transplant recipients with donor-recipient serological Epstein-Barr virus mismatch. Am J Transplant 24: 1486–1494, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 40.

    Zhou K, Gong D, Han Y, Huang W: Role of brentuximab vedotin plus sirolimus in the treatment of classical Hodgkin lymphoma type post-transplant lymphoproliferative disorder: A case-based review. Ann Hematol 103: 2207–2213, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 41.

    Caillard S, Cellot E, Dantal J, Thaunat O, Provot F, Janbon B, French PTLD Registry, et al.: A French cohort study of kidney retransplantation after post-transplant lymphoproliferative disorders. Clin J Am Soc Nephrol 12: 1663–1670, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 42.

    Leeaphorn N, Thongprayoon C, Chewcharat A, Hansrivijit P, Jadlowiec CC, Cummings LS, et al.: Outcomes of kidney retransplantation in recipients with prior posttransplant lymphoproliferative disorders: An analysis of the 2000–2019 UNOS/OPTN database. Am J Transplant 21: 846–853, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 43.

    Van Meerhaeghe T, Murakami N, Moine AL, Brouard S, Sprangers B, Degauque N: Fine-tuning tumor- and allo-immunity: Advances in the use of immune checkpoint inhibitors in kidney transplant recipients. Clin Kidney J 17: sfae061, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 44.

    Rünger A, Schadendorf D, Hauschild A, Gebhardt C: Immune checkpoint blockade for organ-transplant recipients with cancer: A review. Eur J Cancer 175: 326–335, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 45.

    Barnett R, Barta VS, Jhaveri KD: Preserved renal-allograft function and the PD-1 pathway inhibitor nivolumab. N Engl J Med 376: 191–192, 2017 PubMed

  • 46.

    Hailemichael Y, Johnson DH, Abdel-Wahab N, Foo WC, Bentebibel S-E, Daher M, et al.: Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer Cell 40: 509–523.e6, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 47.

    Miao X, Wu Z, Jiang Y, Liu H, Gong W: An efficient combination immunotherapy for antitumor immunity without accelerating cardiac allograft rejection. Immunology 169: 157–166, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 48.

    Khairallah P, Nickolas TL: Bone and mineral disease in kidney transplant recipients. Clin J Am Soc Nephrol 17: 121–130, 2022 PubMed

  • 49.

    Nikkel LE, Mohan S, Zhang A, McMahon DJ, Boutroy S, Dube G, et al.: Reduced fracture risk with early corticosteroid withdrawal after kidney transplant. Am J Transplant 12: 649–659, 2012 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 50.

    Leng Y, Yu X, Yang Y, Xia Y: Efficacy and safety of medications for osteoporosis in kidney transplant recipients or patients with chronic kidney disease: A meta-analysis. J Investig Med 71: 760–772, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 51.

    Zhu P, Yang T, Le J, Fu X, Zhang L: Efficacy of denosumab on bone metabolism and bone mineral density in renal transplant recipients: A systematic review and meta-analysis. Transplant Rev (Orlando) 37: 100793, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 52.

    Cejka D, Benesch T, Krestan C, Roschger P, Klaushofer K, Pietschmann P, et al.: Effect of teriparatide on early bone loss after kidney transplantation. Am J Transplant 8: 1864–1870, 2008 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 53.

    Wang AX, Liu S, Montez-Rath ME, Chertow GM, Lenihan CR: Parathyroidectomy and cinacalcet use in Medicare-insured kidney transplant recipients. Am J Kidney Dis 81: 270–280.e1, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 54.

    Cruzado JM, Moreno P, Torregrosa JV, Taco O, Mast R, Gómez-Vaquero C, et al.: A randomized study comparing parathyroidectomy with cinacalcet for treating hypercalcemia in kidney allograft recipients with hyperparathyroidism. J Am Soc Nephrol 27: 2487–2494, 2016 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 55.

    Wang R, Saad F, McLeod MC, Kew C, Agarwal G, Wille K, et al.: Making the cut: Parathyroidectomy before or after kidney transplantation? World J Surg 47: 319–329, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 56.

    Mohebbi N, Ritter A, Wiegand A, Graf N, Dahdal S, Sidler D, et al.: Sodium bicarbonate for kidney transplant recipients with metabolic acidosis in Switzerland: A multicentre, randomised, single-blind, placebo-controlled, phase 3 trial. Lancet 401: 557–567, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 57.

    United States Renal Data System: 2022 USRDS annual data report: Epidemiology of kidney disease in the United States. Bethesda, MD, National Institute of Diabetes and Digestive and Kidney Diseases, 2022

    • PubMed
    • Export Citation
  • 58.

    Hebert SA, Ibrahim HN: Kidney transplantation in Septuagenarians: 70 is the new 60! Kidney Int Rep 4: 640–642, 2019 PubMed

  • 59.

    Fergie R, Maxwell AP, Cunningham EL: Latest advances in frailty in kidney transplantation: A narrative review. Transplant Rev (Orlando) 38: 100833, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 60.

    Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Cardiovascular Health Study Collaborative Research Group, et al.: Frailty in older adults: Evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56: M146–M156, 2001 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 61.

    Quint EE, Zogaj D, Banning LBD, Benjamens S, Annema C, Bakker SJL, et al.: Frailty and kidney transplantation: A systematic review and meta-analysis. Transplant Direct 7: e701, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 62.

    McAdams-DeMarco MA, Ying H, Olorundare I, King EA, Haugen C, Buta B, et al.: Individual frailty components and mortality in kidney transplant recipients. Transplantation 101: 2126–2132, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 63.

    Harhay MN, Rao MK, Woodside KJ, Johansen KL, Lentine KL, Tullius SG, et al.: An overview of frailty in kidney transplantation: Measurement, management and future considerations. Nephrol Dial Transplant 35: 1099–1112, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 64.

    Zheng J, Cao Y, Wang Z, Nian Y, Guo L, Song W: Frailty and prognosis of patients with kidney transplantation: A meta-analysis. BMC Nephrol 24: 303, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 65.

    McAdams-DeMarco MA, Law A, Tan J, Delp C, King EA, Orandi B, et al.: Frailty, mycophenolate reduction, and graft loss in kidney transplant recipients. Transplantation 99: 805–810, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 66.

    Parajuli S, Astor BC, Lorden HM, O’Toole KA, Wallschlaeger RE, Breyer IC, et al.: Analysis of individual components of frailty: Pre‐transplant grip strength is the strongest predictor of post kidney transplant outcomes. Clin Transplant 36: e14827, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 67.

    McAdams-DeMarco MA, Ying H, Van Pilsum Rasmussen S, Schrack J, Haugen CE, Chu NM, et al.: Prehabilitation prior to kidney transplantation: Results from a pilot study. Clin Transplant 33: e13450, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 68.

    Alfieri C, Malvica S, Cesari M, Vettoretti S, Benedetti M, Cicero E, et al.: Frailty in kidney transplantation: A review on its evaluation, variation and long-term impact. Clin Kidney J 15: 2020–2026, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 69.

    Palmer SC, Ruospo M, Barulli MR, Iurillo A, Saglimbene V, Natale P, COGNITIVE-HD Study Investigators, et al.: COGNITIVE-HD study: Protocol of an observational study of neurocognitive functioning and association with clinical outcomes in adults with end-stage kidney disease treated with haemodialysis. BMJ Open 5: e009328, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 70.

    Chu NM, Gross AL, Shaffer AA, Haugen CE, Norman SP, Xue Q-L, et al.: Frailty and changes in cognitive function after kidney transplantation. J Am Soc Nephrol 30: 336–345, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 71.

    Joshee P, Wood AG, Wood ER, Grunfeld EA: Meta-analysis of cognitive functioning in patients following kidney transplantation. Nephrol Dial Transplant 33: 1268–1277, 2018 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 72.

    Gupta A, Mahnken JD, Bernal J, Sharma P, Lepping RJ, Montgomery RN, et al.: Changes in cognitive function after kidney transplantation: A longitudinal cohort study. Am J Kidney Dis 84: 28–37.e1, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 73.

    Vinke JSJ, Ziengs AL, Buunk AM, van Sonderen L, Gomes-Neto AW, Berger SP, TransplantLines Investigators, et al.: Iron deficiency and cognitive functioning in kidney transplant recipients: Findings of the TransplantLines biobank and cohort study. Nephrol Dial Transplant 38: 1719–1728, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 74.

    Gupta A, Mahnken JD, Johnson DK, Thomas TS, Subramaniam D, Polshak T, et al.: Prevalence and correlates of cognitive impairment in kidney transplant recipients. BMC Nephrol 18: 158, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 75.

    Ziengs AL, Buunk AM, van Sonderen L, Eisenga MF, Gomes Neto AW, Annema C, et al.: Long-term cognitive impairments in kidney transplant recipients: Impact on participation and quality of life. Nephrol Dial Transplant 38: 491–498, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 76.

    McAdams-DeMarco MA, Bae S, Chu N, Gross AL, Brown CH, Oh E, et al.: Dementia and Alzheimer’s disease among older kidney transplant recipients. J Am Soc Nephrol 28: 1575–1583, 2017

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 77.

    Nöhre M, Bauer-Hohmann M, Klewitz F, Kyaw Tha Tun E-M, Tegtbur U, Pape L, et al.: Prevalence and correlates of cognitive impairment in kidney transplant patients using the DEMTECT—Results of a KTX360 substudy. Front Psychiatry 10: 791, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 78.

    Chu NM, Chen X, Gross AL, Carlson MC, Garonzik-Wang JM, Norman SP, et al.: Cognitive impairment burden in older and younger adults across the kidney transplant care continuum. Clin Transplant 35: e14425, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 79.

    Bermond B, Surachno S, Lok A, ten Berge IJM, Plasmans B, Kox C, et al.: Memory functions in prednisone‐treated kidney transplant patients. Clin Transplant 19: 512–517, 2005 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 80.

    Taglialatela G, Rastellini C, Cicalese L: Reduced incidence of dementia in solid organ transplant patients treated with calcineurin inhibitors. J Alzheimers Dis 47: 329–333, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 81.

    Zoccali C, Roumeliotis S, Mallamaci F: Sleep apnea as a cardiorenal risk factor in CKD and renal transplant patients. Blood Purif 50: 642–648, 2021 PubMed

  • 82.

    Mallamaci F, Tripepi R, D’Arrigo G, Panuccio V, Parlongo G, Caridi G, et al.: Sleep‐disordered breathing and 24‐hour ambulatory blood pressure monitoring in renal transplant patients: Longitudinal study. J Am Heart Assoc 9: e016237, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 83.

    Bangalore S, Maron DJ, O’Brien SM, Fleg JL, Kretov EI, Briguori C, ISCHEMIA-CKD Research Group, et al.: Management of coronary disease in patients with advanced kidney disease. N Engl J Med 382: 1608–1618, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 84.

    Nimmo A, Forsyth JL, Oniscu GC, Robb M, Watson C, Fotheringham J, et al.: A propensity score–matched analysis indicates screening for asymptomatic coronary artery disease does not predict cardiac events in kidney transplant recipients. Kidney Int 99: 431–442, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 85.

    Ying T, Tran A, Webster AC, Klarenbach SW, Gill J, Chadban S, et al.: Screening for asymptomatic coronary artery disease in waitlisted kidney transplant candidates: A cost-utility analysis. Am J Kidney Dis 75: 693–704, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 86.

    Ying T, Gill J, Webster A, Kim SJ, Morton R, Klarenbach SW, et al.: Canadian-Australasian randomised trial of screening kidney transplant candidates for coronary artery disease—A trial protocol for the CARSK study. Am Heart J 214: 175–183, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 87.

    Cheng XS, Liu S, Han J, Stedman MR, Baiocchi M, Tan JC, et al.: Association of pretransplant coronary heart disease testing with early kidney transplant outcomes. JAMA Intern Med 183: 134–141, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 88.

    Cheng XS, VanWagner LB, Costa SP, Axelrod DA, Bangalore S, Norman SP, American Heart Association Council on the Kidney in Cardiovascular Disease and Council on Cardiovascular Radiology and Intervention, et al.: Emerging evidence on coronary heart disease screening in kidney and liver transplantation candidates: A scientific statement from the American Heart Association. Circulation 146: e299–e324, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 89.

    Siddiqui MU, Junarta J, Marhefka GD: Coronary revascularization versus optimal medical therapy in renal transplant candidates with coronary artery disease: A systematic review and meta‐analysis. J Am Heart Assoc 11: e023548, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 90.

    Chadban SJ, Ahn C, Axelrod DA, Foster BJ, Kasiske BL, Kher V, et al.: KDIGO clinical practice guideline on the evaluation and management of candidates for kidney transplantation. Transplantation 104: S11–S103, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 91.

    Whelan AM, Ku E: Use of ambulatory blood pressure monitoring in kidney transplant recipients. Nephrol Dial Transplant 34: 1437–1439, 2019 PubMed

  • 92.

    Mallamaci F, Tripepi R, D’Arrigo G, Porto G, Versace MC, Marino C, et al.: Long-term blood pressure monitoring by office and 24-h ambulatory blood pressure in renal transplant patients: A longitudinal study. Nephrol Dial Transplant 34: 1558–1564, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 93.

    Korogiannou M, Sarafidis P, Theodorakopoulou MP, Alexandrou ME, Xagas E, Argyris A, et al.: Sex differences in ambulatory blood pressure levels, control, and phenotypes of hypertension in kidney transplant recipients. J Hypertens 40: 356–363, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 94.

    Wadei HM, Amer H, Taler SJ, Cosio FG, Griffin MD, Grande JP, et al.: Diurnal blood pressure changes one year after kidney transplantation. J Am Soc Nephrol 18: 1607–1615, 2007 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 95.

    Cheung AK, Chang TI, Cushman WC, Furth SL, Hou FF, Ix JH, et al.: Executive summary of the KDIGO 2021 clinical practice guideline for the management of blood pressure in chronic kidney disease. Kidney Int 99: 559–569, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 96.

    Natale P, Mooi PK, Palmer SC, Cross NB, Cooper TE, Webster AC, et al.: Antihypertensive treatment for kidney transplant recipients. Cochrane Database Syst Rev 7: CD003598, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 97.

    Ibrahim HN, Murad DN, Knoll GA: Thinking outside the box: Novel kidney protective strategies in kidney transplantation. Clin J Am Soc Nephrol 16: 1890–1897, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 98.

    Knoll GA, Fergusson D, Chassé M, Hebert P, Wells G, Tibbles LA, et al.: Ramipril versus placebo in kidney transplant patients with proteinuria: A multicentre, double-blind, randomised controlled trial. Lancet Diabetes Endocrinol 4: 318–326, 2016 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 99.

    Ibrahim HN, Jackson S, Connaire J, Matas A, Ney A, Najafian B, et al.: Angiotensin II blockade in kidney transplant recipients. J Am Soc Nephrol 24: 320–327, 2013 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 100.

    Philipp T, Martinez F, Geiger H, Moulin B, Mourad G, Schmieder R, et al.: Candesartan improves blood pressure control and reduces proteinuria in renal transplant recipients: Results from SECRET. Nephrol Dial Transplant 25: 967–976, 2010 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 101.

    Hiremath S, Fergusson DA, Fergusson N, Bennett A, Knoll GA: Renin-angiotensin system blockade and long-term clinical outcomes in kidney transplant recipients: A meta-analysis of randomized controlled trials. Am J Kidney Dis 69: 78–86, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 102.

    Issa N, Ortiz F, Reule SA, Kukla A, Kasiske BL, Mauer M, et al.: The renin–aldosterone axis in kidney transplant recipients and its association with allograft function and structure. Kidney Int 85: 404–415, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 103.

    Mortensen LA, Jespersen B, Helligsoe ASL, Tougaard B, et al.: Effect of spironolactone on kidney function in kidney transplant recipients: A randomized placebo-controlled clinical trial [published online ahead of print Feb 27, 2024]. Clin J Am Soc Nephrol doi:10.2215/cjn.0000000000000439 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 104.

    Chowdhury TA: Post-transplant diabetes mellitus. Clin Med (Lond) 19: 392–395, 2019 PubMed

  • 105.

    Li J, Chong A, Carey S: Dietary interventions on the prevention and management of diabetes in post‐kidney transplantation – A systematic review. Nephrology (Carlton) 27: 269–280, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 106.

    Szumilas K, Wilk A, Szumilas P, Dziedziejko V, Pawlik A: Role of leptin and adiponectin in the pathogenesis of post-transplant diabetes mellitus. Prostaglandins Other Lipid Mediat 174: 106876, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 107.

    Wissing KM, Abramowicz D, Weekers L, Budde K, Rath T, Witzke O, et al.: Prospective randomized study of conversion from tacrolimus to cyclosporine A to improve glucose metabolism in patients with posttransplant diabetes mellitus after renal transplantation. Am J Transplant 18: 1726–1734, 2018 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 108.

    Axelrod DA, Cheungpasitporn W, Bunnapradist S, Schnitzler MA, Xiao H, McAdams-DeMarco M, et al.: Posttransplant diabetes mellitus and immunosuppression selection in older and obese kidney recipients. Kidney Med 4: 100377, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 109.

    Birdwell KA, Park M: Post-transplant cardiovascular disease. Clin J Am Soc Nephrol 16: 1878–1889, 2021 PubMed

  • 110.

    Ramakrishnan P, Garg N, Pabich S, Mandelbrot DA, Swanson KJ: Sodium-glucose cotransporter-2 inhibitor use in kidney transplant recipients. World J Transplant 13: 239–249, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 111.

    Heerspink HJL, Stefánsson BV, Correa-Rotter R, Chertow GM, Greene T, Hou F-F, DAPA-CKD Trial Committees and Investigators, et al.: Dapagliflozin in patients with chronic kidney disease. N Engl J Med 383: 1436–1446, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 112.

    Doehner W, Anker SD, Butler J, Zannad F, Filippatos G, Ferreira JP, et al.: Uric acid and sodium-glucose cotransporter-2 inhibition with empagliflozin in heart failure with reduced ejection fraction: The EMPEROR-reduced trial. Eur Heart J 43: 3435–3446, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 113.

    Zhang L, Zhang F, Bai Y, Huang L, Zhong Y, Zhang X: Effects of sodium-glucose cotransporter-2 (SGLT-2) inhibitors on serum uric acid levels in patients with chronic kidney disease: A systematic review and network meta-analysis. BMJ Open Diabetes Res Care 12: e003836, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 114.

    Sánchez Fructuoso AI, Raba AB, Deras EB, et al.: Sodium-glucose cotransporter-2 inhibitor therapy in kidney transplant patients with type 2 or post-transplant diabetes: An observational multicentre study. Clin Kidney J 16: 1022–1034, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 115.

    Lim J-H, Kwon S, Jeon Y, Kim YH, Kwon H, Kim YS, et al.: The efficacy and safety of SGLT2 inhibitor in diabetic kidney transplant recipients. Transplantation 106: e404–e412, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 116.

    Polychronopoulou E, Bourdon F, Teta D: SGLT2 inhibitors in diabetic and non-diabetic kidney transplant recipients: Current knowledge and expectations. Front Nephrol 4: 1332397, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 117.

    Krisanapan P, Suppadungsuk S, Sanpawithayakul K, Thongprayoon C, Pattharanitima P, Tangpanithandee S, et al.: Safety and efficacy of glucagon-like peptide-1 receptor agonists among kidney transplant recipients: A systematic review and meta-analysis. Clin Kidney J 17: sfae018, 2024 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 118.

    Hicks CW, Bae S, Pozo ME, DiBrito SR, Abularrage CJ, Segev DL, et al.: Practice patterns in arteriovenous fistula ligation among kidney transplant recipients in the United States Renal Data Systems. J Vasc Surg 70: 842–852.e1, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 119.

    Zheng H, Bu S, Song Y, Wang M, Wu J, Chen J: To ligate or not to ligate: A meta-analysis of cardiac effects and allograft function following arteriovenous fistula closure in renal transplant recipients. Ann Vasc Surg 63: 287–292, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 120.

    Rao NN, Stokes MB, Rajwani A, Ullah S, Williams K, King D, et al.: Effects of arteriovenous fistula ligation on cardiac structure and function in kidney transplant recipients. Circulation 139: 2809–2818, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 121.

    Salehi T, Montarello NJ, Juneja N, Stokes MB, Scherer DJ, Williams KF, et al.: Long-term impact of arteriovenous fistula ligation on cardiac structure and function in kidney transplant recipients: A 5-year follow-up observational cohort study. Kidney360 2: 1141–1147, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 122.

    Masson G, Viva T, Huart J, Weekers L, Bonvoisin C, Bouquegneau A, et al.: The effect of elective ligation of the arteriovenous fistula on cardiac and renal functions in kidney transplant recipients. Kidney360 4: 1130–1138, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation

Metrics

All Time Past Year Past 30 Days
Abstract Views 536 536 460
Full Text Views 135 135 117
PDF Downloads 220 220 192