AKI in Pregnancy
By:
Madhusudan Vijayan Barbara T. Murphy Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York

Institute for Critical Care Medicine, Icahn School of Medicine at Mount Sinai, New York, New York

Division of Nephrology, Department of Medicine, Jacobi Medical Center at Albert Einstein College of Medicine, Bronx, New York

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Belinda Jim Barbara T. Murphy Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York

Institute for Critical Care Medicine, Icahn School of Medicine at Mount Sinai, New York, New York

Division of Nephrology, Department of Medicine, Jacobi Medical Center at Albert Einstein College of Medicine, Bronx, New York

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  • 1

    Fisher AL, Nemeth E: Iron homeostasis during pregnancy. Am J Clin Nutr 106[Suppl 6]: 1567S1574S, 2017 PubMed

  • 2

    Soma-Pillay P, Nelson-Piercy C, Tolppanen H, Mebazaa A: Physiological changes in pregnancy. Cardiovasc J Afr 27: 8994, 2016 PubMed

  • 3

    Hunter S, Robson SC: Adaptation of the maternal heart in pregnancy. Br Heart J 68: 540543, 1992 PubMed

  • 4

    Sanghavi M, Rutherford JD: Cardiovascular physiology of pregnancy. Circulation 130: 10031008, 2014 PubMed

  • 5

    Conrad KP: Emerging role of relaxin in the maternal adaptations to normal pregnancy: implications for preeclampsia. Semin Nephrol 31: 1532, 2011 PubMed

  • 6

    Conrad KP, Jeyabalan A, Danielson LA, Kerchner LJ, Novak J: Role of relaxin in maternal renal vasodilation of pregnancy. Ann N Y Acad Sci 1041: 147154, 2005 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7

    Irani RA, Xia Y: Renin angiotensin signaling in normal pregnancy and preeclampsia. Semin Nephrol 31: 4758, 2011 PubMed

  • 8

    Rasmussen PE, Nielsen FR: Hydronephrosis during pregnancy: A literature survey. Eur J Obstet Gynecol Reprod Biol 27: 249259, 1988 PubMed

  • 9

    Higby K, Suiter CR, Phelps JY, Siler-Khodr T, Langer O: Normal values of urinary albumin and total protein excretion during pregnancy. Am J Obstet Gynecol 171: 984989, 1994 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10

    Odutayo A, Hladunewich M: Obstetric nephrology: Renal hemodynamic and metabolic physiology in normal pregnancy. Clin J Am Soc Nephrol 7: 20732080, 2012 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11

    Harel Z, McArthur E, Hladunewich M, Dirk JS, Wald R, Garg AX, et al: Serum creatinine levels before, during, and after pregnancy. JAMA 321: 205207, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12

    Nguyen MT, Maynard SE, Kimmel PL: Misapplications of commonly used kidney equations: Renal physiology in practice. Clin J Am Soc Nephrol 4: 528534, 2009 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 13

    Smith MC, Moran P, Davison JM: EPI-CKD is a poor predictor of GFR in pregnancy. Arch Dis Child Fetal Neonatal Ed 96: Fa99, 2011

  • 14

    Kristensen K, Larsson I, Hansson SR: Increased cystatin C expression in the pre-eclamptic placenta. Mol Hum Reprod 13: 189195, 2007 PubMed

  • 15

    Bellos I, Fitrou G, Daskalakis G, Papantoniou N, Pergialiotis V: Serum cystatin-c as predictive factor of preeclampsia: A meta-analysis of 27 observational studies. Pregnancy Hypertens 16: 97104, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16

    Champion ML, Becker DA, McIlwraith C, Blanchard CT, Szychowski JM, Kim DJ, et al: Contemporary test performance of the random urine protein-to-creatinine ratio. Am J Perinatol Published May 6, 2022 10.1055/a-1786-8847. Online ahead of print PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 17

    Ekiz A, Kaya B, Polat I, Avci ME, Ozkose B, Kicik Caliskan R, et al: The outcome of pregnancy with new onset proteinuria without hypertension: Retrospective observational study. J Matern Fetal Neonatal Med 29: 17651769, 2016 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 18

    Akaishi R, Yamada T, Morikawa M, Nishida R, Minakami H: Clinical features of isolated gestational proteinuria progressing to pre-eclampsia: Retrospective observational study. BMJ Open 4: e004870, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 19

    Kreepala C, Srila-On A, Kitporntheranunt M, Anakkamatee W, Lawtongkum P, Wattanavaekin K: The association between GFR evaluated by serum cystatin C and proteinuria during pregnancy. Kidney Int Rep 4: 854863, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 20

    Shah S, Meganathan K, Christianson AL, Harrison K, Leonard AC, Thakar CV: Pregnancy-related acute kidney injury in the United States: Clinical outcomes and health care utilization. Am J Nephrol 51: 216226, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 21

    Mehrabadi A, Liu S, Bartholomew S, Hutcheon JA, Magee LA, Kramer MS, et al; Canadian Perinatal Surveillance System Public Health Agency of Canada: Hypertensive disorders of pregnancy and the recent increase in obstetric acute renal failure in Canada: Population based retrospective cohort study. BMJ 349: g4731, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 22

    Prakash J, Pant P, Prakash S, Sivasankar M, Vohra R, Doley PK, et al: Changing picture of acute kidney injury in pregnancy: Study of 259 cases over a period of 33 years. Indian J Nephrol 26: 262267, 2016 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 23

    Sahay M, Priyashree, Dogra L, Ismal K, Vali S: Pregnancy-related acute kidney injury in public hospital in South India: Changing trends. J Assoc Physicians India 70: 1112, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 24

    Huang C, Chen S: Acute kidney injury during pregnancy and puerperium: A retrospective study in a single center. BMC Nephrol 18: 146, 2017 PubMed

  • 25

    Liu Y-m, Bao H-d, Jiang Z-z, Huang Y-j, Wang N-s: Pregnancy-related acute kidney injury and a review of the literature in China. Intern Med 54: 16951703, 2015

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 26

    Liu D, He W, Li Y, Xiong M, Wang L, Huang J, et al: Epidemiology of acute kidney injury in hospitalized pregnant women in China. BMC Nephrol 20: 67, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 27

    Beers K, Wen HH, Saha A, Chauhan K, Dave M, Coca S, et al: Racial and ethnic disparities in pregnancy-related acute kidney injury. Kidney360 1: 169178, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 28

    Gama RM, Bhaduri M, Atkins W, Nwankiti MK, Hutchison G, Thomas M, et al: Ethnic disparities in pregnancy-related acute kidney injury in a United Kingdom population. J Nephrol 36: 777787, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 29

    Zhang Y, Cantor RM, MacGibbon K, Romero R, Goodwin TM, Mullin PM, et al: Familial aggregation of hyperemesis gravidarum. Am J Obstet Gynecol 204: 230.e1230.e7, 2011 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 30

    Shim S, Ryu A, Kim Y: Acute kidney injury arising from severe hyperemesis gravidarum: Case report with a review of literatures. Soonchunhyang Med Sci 21: 2830, 2015

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 31

    Connolly A, Thorp JM Jr: Urinary tract infections in pregnancy. Urol Clin North Am 26: 779787, 1999 PubMed

  • 32

    Schnarr J, Smaill F: Asymptomatic bacteriuria and symptomatic urinary tract infections in pregnancy. Eur J Clin Invest 38[Suppl 2]: 5057, 2008 PubMed

  • 33

    American Academy of Pediatrics ACoOa: Gynecologists: Guidelines for perinatal care, 7th Ed.: Elk Grove Village, 2012.

  • 34

    Hill JB, Sheffield JS, McIntire DD, Wendel GD Jr: Acute pyelonephritis in pregnancy. Obstet Gynecol 105: 1823, 2005 PubMed

  • 35

    Kazemier BM, Koningstein FN, Schneeberger C, Ott A, Bossuyt PM, de Miranda E, et al: Maternal and neonatal consequences of treated and untreated asymptomatic bacteriuria in pregnancy: a prospective cohort study with an embedded randomised controlled trial. Lancet Infect Dis 15: 13241333, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 36

    United States Preventive Services Task Force: Final Recommendation Statement. Asymptomatic Bacteriuria in Adults: Screening [Internet]. Available from: https://www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/asymptomatic-bacteriuria-in-adults-screening. Accessed June 7, 2023.

    • PubMed
    • Export Citation
  • 37

    Nicolle LE, Gupta K, Bradley SF, Colgan R, DeMuri GP, Drekonja D, et al: Clinical practice guideline for the management of asymptomatic bacteriuria: 2019 update by the Infectious Diseases Society of America. Clin Infect Dis 68: e83e110, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 38

    UK National Screening Committee: Antenatal screening Programme. Asymptomatic bacteriuria. https://view-health-screening-recommendations.service.gov.uk/asymptomatic-bacteriuria/. Accessed June 15, 2023

    • PubMed
    • Export Citation
  • 39

    National Institute for Health and Care Excellence (NICE): Urinary tract infection (lower): Antimicrobial prescribing: NICE guideline. 2018. https://www.nice.org.uk/guidance/ng109. Accessed June 15, 2023

    • PubMed
    • Export Citation
  • 40

    Smaill FM, Vazquez JC: Antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane Database Syst Rev 2019: CD000490, 2019 PubMed

  • 41

    Grette K, Cassity S, Holliday N, Rimawi BH: Acute pyelonephritis during pregnancy: A systematic review of the aetiology, timing, and reported adverse perinatal risks during pregnancy. J Obstet Gynaecol 40: 739748, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 42

    Vijayan M, Avendano M, Chinchilla KA, Jim B: Acute kidney injury in pregnancy. Curr Opin Crit Care 25: 580590, 2019 PubMed

  • 43

    Giouleka S, Boureka E, Tsakiridis I, Lallas K, Papazisis G, Mamopoulos A, et al: Sepsis in pregnancy and the puerperium: A comparative review of major guidelines. Obstet Gynecol Surv 78: 237248, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 44

    Moyer A, Chakravarty EF: Management of pregnancy in lupus. Rheum Dis Clin North Am 47: 441455, 2021 PubMed

  • 45

    Buyon JP, Kim MY, Guerra MM, Lu S, Reeves E, Petri M, et al: Kidney outcomes and risk factors for nephritis (flare/de novo) in a multiethnic cohort of pregnant patients with lupus. Clin J Am Soc Nephrol 12: 940946, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 46

    Chen Y, Li K, Zhang H, Liu Z, Chen D, Yang L, et al. Good pregnancy outcomes in lupus nephritis patients with complete renal remission. Nephrol Dial Transplant 37: 18881894, 2022.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 47

    Sturfelt G, Sjöholm AG: Complement components, complement activation, and acute phase response in systemic lupus erythematosus. Int Arch Allergy Appl Immunol 75: 7583, 1984 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 48

    He WR, Wei H: Maternal and fetal complications associated with systemic lupus erythematosus: An updated meta-analysis of the most recent studies (2017–2019). Medicine (Baltimore) 99: e19797, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 49

    Clowse MEB, Magder L, Witter F, Petri M: Hydroxychloroquine in lupus pregnancy. Arthritis Rheum 54: 36403647, 2006 PubMed

  • 50

    Levy RA, Gonzalez-Rivera T, Khamashta M, Fox NL, Jones-Leone A, Rubin B, et al: 10 Years of belimumab experience: What have we learnt? Lupus 30: 17051721, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 51

    Highlights of Prescribing Information. Food and Drug Administration [Internet]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/213716s000lbl.pdf. Accessed June 7, 2023

    • PubMed
    • Export Citation
  • 52

    Furie RA, Aroca G, Cascino MD, Garg JP, Rovin BH, Alvarez A, et al: B-cell depletion with obinutuzumab for the treatment of proliferative lupus nephritis: A randomised, double-blind, placebo-controlled trial. Ann Rheum Dis 81: 100107, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 53

    Alrahmani L, Willrich MAV: The complement alternative pathway and preeclampsia. Curr Hypertens Rep 20: 40, 2018 PubMed

  • 54

    Holmes CH, Simpson KL, Okada H, Okada N, Wainwright SD, Purcell DF, et al: Complement regulatory proteins at the feto-maternal interface during human placental development: distribution of CD59 by comparison with membrane cofactor protein (CD46) and decay accelerating factor (CD55). Eur J Immunol 22: 15791585, 1992 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 55

    Amari Chinchilla K, Vijayan M, Taveras Garcia B, Jim B: Complement-mediated disorders in pregnancy. Adv Chronic Kidney Dis 27: 155164, 2020 PubMed

  • 56

    Huerta A, Arjona E, Portoles J, Lopez-Sanchez P, Rabasco C, Espinosa M, et al: A retrospective study of pregnancy-associated atypical hemolytic uremic syndrome. Kidney Int 93: 450459, 2018 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 57

    Fakhouri F, Scully M, Ardissino G, Al-Dakkak I, Miller B, Rondeau E: Pregnancy-triggered atypical hemolytic uremic syndrome (aHUS): A Global aHUS Registry analysis. J Nephrol 34: 15811590, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 58

    Socié G, Caby-Tosi MP, Marantz JL, Cole A, Bedrosian CL, Gasteyger C, et al: Eculizumab in paroxysmal nocturnal haemoglobinuria and atypical haemolytic uraemic syndrome: 10-year pharmacovigilance analysis. Br J Haematol 185: 297310, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 59

    Sarno L, Tufano A, Maruotti GM, Martinelli P, Balletta MM, Russo D: Eculizumab in pregnancy: A narrative overview. J Nephrol 32: 1725, 2019 PubMed

  • 60

    Fakhouri F, Fila M, Hummel A, Ribes D, Sellier-Leclerc AL, Ville S, et al: Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: A prospective multicenter study. Blood 137: 24382449, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 61

    Bartsch E, Medcalf KE, Park AL, Ray JG; High Risk of Pre-eclampsia Identification Group: Clinical risk factors for pre-eclampsia determined in early pregnancy: Systematic review and meta-analysis of large cohort studies. BMJ 353: i1753, 2016 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 62

    Magee LA, Brown MA, Hall DR, Gupte S, Hennessy A, Karumanchi SA, et al: The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice. Pregnancy Hypertens 27: 148169, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 63

    Sovio U, Gaccioli F, Cook E, Hund M, Charnock-Jones DS, Smith GCS. Prediction of preeclampsia using the soluble fms-like tyrosine kinase 1 to placental growth factor ratio: A prospective cohort study of unselected nulliparous women. Hypertens Dallas Tex 69: 731738, 1979

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 64

    Suresh S, Patel E, Mueller A, Morgan J, Lewandowski WL, Verlohren S, et al: The additive role of angiogenic markers for women with confirmed preeclampsia. Am J Obstet Gynecol 228: 573.e1573.e11, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 65

    Verlohren S, Brennecke SP, Galindo A, Karumanchi SA, Mirkovic LB, Schlembach D, et al: Clinical interpretation and implementation of the sFlt-1/PlGF ratio in the prediction, diagnosis and management of preeclampsia. Pregnancy Hypertens 27: 4250, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 66

    Nelson DB, Byrne JJ, Cunningham FG: Acute fatty liver of pregnancy. Obstet Gynecol 137: 535546, 2021 PubMed

  • 67

    Ibdah JA: Acute fatty liver of pregnancy: An update on pathogenesis and clinical implications. World J Gastroenterol 12: 73977404, 2006 PubMed

  • 68

    Tran TT, Ahn J, Reau NS: ACG clinical guideline: liver disease and pregnancy. Am J Gastroenterol 111: 176194, quiz 196, 2016 PubMed

  • 69

    Natarajan SK, Ibdah JA: Role of 3-hydroxy fatty acid-induced hepatic lipotoxicity in acute fatty liver of pregnancy. Int J Mol Sci 19: 322, 2018 PubMed

  • 70

    Rector RS, Ibdah JA: Fatty acid oxidation disorders: Maternal health and neonatal outcomes. Semin Fetal Neonatal Med 15: 122128, 2010 PubMed

  • 71

    Byrne JJ, Seasely A, Nelson DB, Mcintire DD, Cunningham FG: Comparing acute fatty liver of pregnancy from hemolysis, elevated liver enzymes, and low platelets syndrome. J Matern Fetal Neonatal Med 35: 13521362, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 72

    Ch’ng CL, Morgan M, Hainsworth I, Kingham JGC: Prospective study of liver dysfunction in pregnancy in Southwest Wales. Gut 51: 876880, 2002 PubMed

  • 73

    Goel A, Ramakrishna B, Zachariah U, Ramachandran J, Eapen CE, Kurian G, et al: How accurate are the Swansea criteria to diagnose acute fatty liver of pregnancy in predicting hepatic microvesicular steatosis? Gut 60: 138139, author reply 139–140, 2011 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 74

    Jena M, Mitch WE: Rapidly reversible acute renal failure from ureteral obstruction in pregnancy. Am J Kidney Dis 28: 457460, 1996 PubMed

  • 75

    Cabiddu G, Castellino S, Gernone G, Santoro D, Giacchino F, Credendino O, et al; Kidney and Pregnancy Study Group of Italian Society of Nephrology: Best practices on pregnancy on dialysis: The Italian Study Group on Kidney and Pregnancy. J Nephrol 28: 279288, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 76

    Hladunewich MA, Hou S, Odutayo A, Cornelis T, Pierratos A, Goldstein M, et al: Intensive hemodialysis associates with improved pregnancy outcomes: A Canadian and United States cohort comparison. J Am Soc Nephrol 25: 11031109, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 77

    Chen TK, Gelber AC, Witter FR, Petri M, Fine DM: Renal biopsy in the management of lupus nephritis during pregnancy. Lupus 24: 147154, 2015 PubMed

  • 78

    Packham D, Fairley KF: Renal biopsy: Indications and complications in pregnancy. Br J Obstet Gynaecol 94: 935939, 1987 PubMed

  • 79

    Day C, Hewins P, Hildebrand S, Sheikh L, Taylor G, Kilby M, et al. The role of renal biopsy in women with kidney disease identified in pregnancy. Nephrol Dial Transplant 23: 201206, 2008

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 80

    Piccoli GB, Daidola G, Attini R, Parisi S, Fassio F, Naretto C, et al: Kidney biopsy in pregnancy: evidence for counselling? A systematic narrative review. BJOG 120: 412427, 2013 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 81

    Farrington CA: Kidney imaging and biopsy in pregnancy. Adv Chronic Kidney Dis 27: 525530, 2020 PubMed

  • 82

    Liu Y, Ma X, Zheng J, Liu X, Yan T: Pregnancy outcomes in patients with acute kidney injury during pregnancy: A systematic review and meta-analysis. BMC Pregnancy Childbirth 17: 235, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 83

    Trakarnvanich T, Ngamvichchukorn T, Susantitaphong P: Incidence of acute kidney injury during pregnancy and its prognostic value for adverse clinical outcomes: A systematic review and meta-analysis. Medicine (Baltimore) 101: e29563, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 84

    Conti-Ramsden FI, Nathan HL, De Greeff A, Hall DR, Seed PT, Chappell LC, et al. Pregnancy-related acute kidney injury in preeclampsia: Risk factors and renal outcomes. Hypertens Dallas Tex 74: 11441151, 2019

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 85

    Wang L, Tang D, Zhao H, Lian M: Evaluation of risk and prognosis factors of acute kidney injury in patients with HELLP syndrome during pregnancy. Front Physiol 12: 650826, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 86

    Tangren JS, Powe CE, Ankers E, Ecker J, Bramham K, Hladunewich MA, et al: Pregnancy outcomes after clinical recovery from AKI. J Am Soc Nephrol 28: 15661574, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 87

    Tangren JS, Wan Md Adnan WAH, Powe CE, Ecker J, Bramham K, Hladunewich MA, et al. Risk of preeclampsia and pregnancy complications in women with a history of acute kidney injury. Hypertens Dallas Tex 72: 451459, 2018

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 88

    Gillis EE, Brands MW, Sullivan JC: Adverse maternal and fetal outcomes in a novel experimental model of pregnancy after recovery from renal ischemia-reperfusion injury. J Am Soc Nephrol 32: 375384, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 89

    Shapiro J, Ray JG, McArthur E, Jeyakumar N, Chanchlani R, Harel Z, et al: Risk of acute kidney injury after hypertensive disorders of pregnancy: A population-based cohort study. Am J Kidney Dis 79: 561569, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 90

    Verma SK, Molitoris BA: Renal endothelial injury and microvascular dysfunction in acute kidney injury. Semin Nephrol 35: 96107, 2015 PubMed

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