Non–Drug-Related Interstitial Nephritis
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Oshorenua Aiyegbusi Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada

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Ivette Ruiz-Leija Nephrology Department, Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico

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  • 1.

    Praga M, González E: Acute interstitial nephritis. Kidney Int 77: 956961, 2010 PubMed

  • 2.

    Councilman WT: Acute interstitial nephritis. J Exp Med 3: 393420, 1898 PubMed

  • 3.

    Kimmelstiel P: Acute hematogenous interstitial nephritis. Am J Pathol 14: 737761, 1938 PubMed

  • 4.

    Praga M, Sevillano A, Auñón P, González E: Changes in the aetiology, clinical presentation and management of acute interstitial nephritis, an increasingly common cause of acute kidney injury. Nephrol Dial Transplant 30: 14721479, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5.

    Muriithi AK, Leung N, Valeri AM, Cornell LD, Sethi S, Fidler ME, et al.: Biopsy-proven acute interstitial nephritis, 1993–2011: A case series. Am J Kidney Dis 64: 558566, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6.

    Nast CC: Medication-induced interstitial nephritis in the 21st century. Adv Chronic Kidney Dis 24: 7279, 2017 PubMed

  • 7.

    Goicoechea M, Rivera F, López-Gómez JM; Spanish Registry of Glomerulonephritis: Increased prevalence of acute tubulointerstitial nephritis. Nephrol Dial Transplant 28: 112115, 2013 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8.

    Aiyegbusi O, McGregor L, McGeoch L, Kipgen D, Geddes CC, Stevens KI: Renal disease in primary Sjögren’s syndrome. Rheumatol Ther 8: 6380, 2021 PubMed

  • 9.

    Muriithi AK, Nasr SH, Leung N: Utility of urine eosinophils in the diagnosis of acute interstitial nephritis. Clin J Am Soc Nephrol 8: 18571862, 2013 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10.

    Braden GL, O’Shea MH, Mulhern JG: Tubulointerstitial diseases. Am J Kidney Dis 46: 560572, 2005 PubMed

  • 11.

    Perazella MA: Clinical approach to diagnosing acute and chronic tubulointerstitial disease. Adv Chronic Kidney Dis 24: 5763, 2017 PubMed

  • 12.

    Fogo AB, Lusco MA, Najafian B, Alpers CE: AJKD Atlas of Renal Pathology: Acute Interstitial Nephritis. Am J Kidney Dis 67: e35e36, 2016 PubMed

  • 13.

    Floege Jurgen JRJ: Feehally John. Comprehensive Clinical Nephrology, 4th Ed., Elsevier, 2010

  • 14.

    Neilson EG: Pathogenesis and therapy of interstitial nephritis. Kidney Int 35: 12571270, 1989 PubMed

  • 15.

    Caravaca-Fontán F, Fernández-Juárez G, Praga M: Acute kidney injury in interstitial nephritis. Curr Opin Crit Care 25: 558564, 2019 PubMed

  • 16.

    Lusco MA, Fogo AB, Najafian B, Alpers CE: AJKD atlas of renal pathology: Anti-tubular basement membrane antibody disease. Am J Kidney Dis 70: e3e4, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 17.

    Dixon AJ, Winearls CG, Dunnill MS: Interstitial nephritis. J Clin Pathol 34: 616624, 1981 PubMed

  • 18.

    Hodgkins KS, Schnaper HW: Tubulointerstitial injury and the progression of chronic kidney disease. Pediatr Nephrol 27: 901909, 2012 PubMed

  • 19.

    Raghavan R, Eknoyan G: Acute interstitial nephritis—a reappraisal and update. Clin Nephrol 82: 149162, 2014 PubMed

  • 20.

    Raina R, Ale S, Chaturvedi T, Fraley L, Novak R, Tanphaichitr N: Infection associated acute interstitial nephritis; a case report. J Nephropathol 6: 5357, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 21.

    Anumudu S, Eknoyan G: Pyelonephritis: A Historical Reappraisal. J Am Soc Nephrol 30: 914917, 2019 PubMed

  • 22.

    Li L, Parwani AV: Xanthogranulomatous pyelonephritis. Arch Pathol Lab Med 135: 671674, 2011 PubMed

  • 23.

    Caers J, Peeters P, Vanden Houte K, Sennesael J, Van der Niepen P, Verbeelen D: Acute interstitial nephritis associated with salmonellosis. Eur J Intern Med 17: 217219, 2006 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 24.

    Organization GdWH: Global tuberculosis report 2022 [Available from: https://www.who.int/teams/global-tuberculosis-programme/tb-reports.

    • PubMed
    • Export Citation
  • 25.

    Chapagain A, Dobbie H, Sheaff M, Yaqoob MM: Presentation, diagnosis, and treatment outcome of tuberculous-mediated tubulointerstitial nephritis. Kidney Int 79: 671677, 2011 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 26.

    Ball S, Cook T, Hulme B, Palmer A, Taube D: The diagnosis and racial origin of 394 patients undergoing renal biopsy: an association between Indian race and interstitial nephritis. Nephrol Dial Transplant 12: 7177, 1997 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 27.

    Furuto Y, Hashimoto H, Kawamura M, Yamashita J, Yoshikawa T, Namikawa A, et al.: Acute tubulointerstitial nephritis in a patient with early bronchial tuberculosis. J Formos Med Assoc 121: 557562, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 28.

    Shribman JH, Eastwood JB, Uff J: Immune complex nephritis complicating miliary tuberculosis. Br Med J (Clin Res Ed) 287: 15931594, 1983 PubMed

  • 29.

    Veer M, Abdulmassih R, Como J, Min Z, Bhanot N. Adenoviral nephritis in a renal transplant recipient: Case report and literature review. Transpl Infect Dis August: 19, 2017

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 30.

    Milosevski-Lomić G, Marković-Lipkovski J, Kostić M, Dusan Paripović, Spasojević-Dimitrijeva B, Peco-Antić A: Granulomatous interstitial nephritis associated with influenza A: H1N1 infection--A case report. Srp Arh Celok Lek 144: 215218, 2016 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 31.

    León-Román J, Agraz I, Vergara A, Ramos N, Toapanta N, García-Carro C, et al.: COVID-19 infection and renal injury: Where is the place for acute interstitial nephritis disease? Clin Kidney J 15: 16981704, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 32.

    Ng JH, Bijol V, Sparks MA, Sise ME, Izzedine H, Jhaveri KD: Pathophysiology and pathology of acute kidney injury in patients with COVID-19. Adv Chronic Kidney Dis 27: 365376, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 33.

    Melendez Rivera JG, Hashmi MF: HIV Nephropathy, Treasure Island, FL, StatPearls, 2022

  • 34.

    Zaidan M, Lescure FX, Brochériou I, Dettwiler S, Guiard-Schmid JB, Pacanowski J, et al.: Tubulointerstitial nephropathies in HIV-infected patients over the past 15 years: A clinico-pathological study. Clin J Am Soc Nephrol 8: 930938, 2013 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 35.

    Do Vale CL, Naicker S, Lippincott CK: Acute interstitial nephritis in tuberculosis-associated immune reconstitution inflammatory syndrome. Kidney Int Rep 7: 920923, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 36.

    Doi A, Iwata K, Hara S, Imai Y, Hasuike T, Nishioka H: Interstitial nephritis caused by HIV infection by itself: A case report. Int J Gen Med 9: 311314, 2016 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 37.

    Swanson KJ, Djamali A, Jorgenson MR, Misch EA, Ghaffar A, Zhong W, et al. Cytomegalovirus nephritis in kidney transplant recipients: Epidemiology and outcomes of an uncommon diagnosis. Transpl Infect Dis 23: e13702, 2021.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 38.

    Sekulic M, Crary GS, Herrera Hernandez LP: BK polyomavirus tubulointerstitial nephritis with urothelial hyperplasia in a kidney transplant. Am J Kidney Dis 68: 307311, 2016 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 39.

    Inaba H, Jones DP, Gaber LW, Shenep JL, Call SK, Pui CH, et al.: BK virus-induced tubulointerstitial nephritis in a child with acute lymphoblastic leukemia. J Pediatr 151: 215217, 2007 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 40.

    Hoefele J, Rüssmann D, Klein B, Weber LT, Führer M: BK virus induced nephritis in a boy with acute myeloid leukaemia undergoing bone marrow transplantation. NDT Plus 1: 336339, 2008 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 41.

    Preddie DC, Markowitz GS, Radhakrishnan J, Nickolas TL, D’Agati VD, Schwimmer JA, et al.: Mycophenolate mofetil for the treatment of interstitial nephritis. Clin J Am Soc Nephrol 1: 718722, 2006 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 42.

    Caravaca-Fontán F, Shabaka A, Sánchez-Álamo B, de Lorenzo A, Díaz M, Blasco M, et al.: Spanish Group for the Study of Glomerular Diseases (GLOSEN): Recurrent acute interstitial nephritis: What lies beneath. Clin Kidney J 14: 197204, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 43.

    Ren H, Wang WM, Chen XN, Zhang W, Pan XX, Wang XL, et al.: Renal involvement and followup of 130 patients with primary Sjögren’s syndrome. J Rheumatol 35: 278284, 2008 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 44.

    Maripuri S, Grande JP, Osborn TG, Fervenza FC, Matteson EL, Donadio JV, et al.: Renal involvement in primary Sjögren’s syndrome: A clinicopathologic study. Clin J Am Soc Nephrol 4: 14231431, 2009 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 45.

    Matsumura R, Kondo Y, Sugiyama T, Sueishi M, Koike T, Takabayashi K, et al.: Immunohistochemical identification of infiltrating mononuclear cells in tubulointerstitial nephritis associated with Sjögren’s syndrome. Clin Nephrol 30: 335340, 1988 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 46.

    Bossini N, Savoldi S, Franceschini F, Mombelloni S, Baronio M, Cavazzana I, et al.: Clinical and morphological features of kidney involvement in primary Sjögren’s syndrome. Nephrol Dial Transplant 16: 23282336, 2001 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 47.

    Kidder D, Rutherford E, Kipgen D, Fleming S, Geddes C, Stewart GA: Kidney biopsy findings in primary Sjögren syndrome. Nephrol Dial Transplant 30: 13631369, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 48.

    Goules A, Geetha D, Arend LJ, Baer AN. Renal involvement in primary Sjogren’s syndrome: Natural history and treatment outcome. Clin Exp Rheumatol 37(Suppl 118): 123132, 2019

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 49.

    Shen Y, Xie J, Lin L, Li X, Shen P, Pan X, et al.: Combination cyclophosphamide/glucocorticoids provide better tolerability and outcomes versus glucocorticoids alone in patients with Sjogren’s associated chronic interstitial nephritis. Am J Nephrol 46: 473480, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 50.

    Kamata Y, Sato H, Joh K, Tsuchiya Y, Kunugi S, Shimizu A, et al.: Clinical characteristics of biopsy-proven renal sarcoidosis in Japan. Sarcoidosis Vasc Diffuse Lung Dis 35: 252260, 2018 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 51.

    Rajakariar R, Sharples EJ, Raftery MJ, Sheaff M, Yaqoob MM: Sarcoid tubulo-interstitial nephritis: long-term outcome and response to corticosteroid therapy. Kidney Int 70: 165169, 2006 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 52.

    Oliva-Damaso N, Oliva-Damaso E, Payan J: Acute and chronic tubulointerstitial nephritis of rheumatic causes. Rheum Dis Clin North Am 44: 619633, 2018 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 53.

    Mahévas M, Lescure FX, Boffa JJ, Delastour V, Belenfant X, Chapelon C, et al.: Renal sarcoidosis: clinical, laboratory, and histologic presentation and outcome in 47 patients. Medicine (Baltimore) 88: 98106, 2009 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 54.

    Löffler C, Löffler U, Tuleweit A, Waldherr R, Uppenkamp M, Bergner R: Renal sarcoidosis: epidemiological and follow-up data in a cohort of 27 patients. Sarcoidosis Vasc Diffuse Lung Dis 31: 306315, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 55.

    Mahevas M, Audard V, Rousseau A, Cez A, Guerrot D, Verhelst D, et al; GSF French Sarcoidosis Group: Efficacy and safety of methylprednisolone pulse followed by oral prednisone vs. oral prednisone alone in sarcoidosis tubulointerstitial nephritis: a randomized, open-label, controlled clinical trial. Nephrol Dial Transplant 38: 961968, 2023 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 56.

    Hilderson I, Van Laecke S, Wauters A, Donck J: Treatment of renal sarcoidosis: is there a guideline? Overview of the different treatment options. Nephrol Dial Transplant 29: 18411847, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 57.

    Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, et al.: Consensus statement on the pathology of IgG4-related disease. Mod Pathol 25: 11811192, 2012 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 58.

    Raissian Y, Nasr SH, Larsen CP, Colvin RB, Smyrk TC, Takahashi N, et al.: Diagnosis of IgG4-related tubulointerstitial nephritis. J Am Soc Nephrol 22: 13431352, 2011 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 59.

    Saeki T, Nishi S, Imai N, Ito T, Yamazaki H, Kawano M, et al.: Clinicopathological characteristics of patients with IgG4-related tubulointerstitial nephritis. Kidney Int 78: 10161023, 2010 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 60.

    Carruthers MN, Topazian MD, Khosroshahi A, Witzig TE, Wallace ZS, Hart PA, et al.: Rituximab for IgG4-related disease: A prospective, open-label trial. Ann Rheum Dis 74: 11711177, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 61.

    Park MH, D’Agati V, Appel GB, Pirani CL. Tubulointerstitial disease in lupus nephritis: relationship to immune deposits, interstitial inflammation, glomerular changes, renal function, and prognosis. 44: 399403, 1986

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 62.

    Yu F, Wu LH, Tan Y, Li LH, Wang CL, Wang WK, et al.: Tubulointerstitial lesions of patients with lupus nephritis classified by the 2003 International Society of Nephrology and Renal Pathology Society system. Kidney Int 77: 820829, 2010 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 63.

    Lan-Ting H, You-Ming C, Li-Xin W, Chen W, Xiao-Yan Z, Hong-Yan H: Clinicopathological factors for tubulointerstitial injury in lupus nephritis. Clin Rheumatol 39: 16171626, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 64.

    Mori Y, Kishimoto N, Yamahara H, Kijima Y, Nose A, Uchiyama-Tanaka Y, et al.: Predominant tubulointerstitial nephritis in a patient with systemic lupus nephritis. Clin Exp Nephrol 9: 7984, 2005 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 65.

    Omokawa A, Wakui H, Okuyama S, Togashi M, Ohtani H, Komatsuda A, et al.: Predominant tubulointerstitial nephritis in a patient with systemic lupus erythematosus: Phenotype of infiltrating cells. Clin Nephrol 69: 436444, 2008 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 66.

    Singh AK, Ucci A, Madias NE: Predominant tubulointerstitial lupus nephritis. Am J Kidney Dis 27: 273278, 1996 PubMed

  • 67.

    Andres GA, McCluskey RT: Tubular and interstitial renal disease due to immunologic mechanisms. Kidney Int 7: 271289, 1975 PubMed

  • 68.

    Nasr SH, Leung N, Said SM, Alkhateeb HB, Madden BJ, Charlesworth MC, et al.: Membranous nephropathy with extensive tubular basement membrane deposits following allogeneic hematopoietic cell transplant: A report of 5 cases. Am J Kidney Dis 79: 904908, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 69.

    Dobrin RS, Vernier RL, Fish AL: Acute eosinophilic interstitial nephritis and renal failure with bone marrow-lymph node granulomas and anterior uveitis. A new syndrome. Am J Med 59: 325333, 1975 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 70.

    Heaney A, McLoone E, Williams M, Silvestri G, Courtney AE, O’Rourke D, et al.: Tubulointerstitial nephritis and uveitis in Northern Ireland. Eye (Lond) 36: 16451650, 2022 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 71.

    Levinson RD, Park MS, Rikkers SM, Reed EF, Smith JR, Martin TM, et al.: Strong associations between specific HLA-DQ and HLA-DR alleles and the tubulointerstitial nephritis and uveitis syndrome. Invest Ophthalmol Vis Sci 44: 653657, 2003 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 72.

    Ruebner RL, Fadrowski JJ: Tubulointerstitial nephritis. Pediatr Clin North Am 66: 111119, 2019 PubMed

  • 73.

    Sinnamon KT, Courtney AE, Harron C, O’Rourke DM, Mullan RN: Tubulointerstitial nephritis and uveitis (TINU) syndrome: Epidemiology, diagnosis and management. NDT Plus 1: 112116, 2008 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 74.

    Corica D, Romano C: Renal involvement in inflammatory bowel diseases. J Crohn’s Colitis 10: 226235, 2016 PubMed

  • 75.

    Ambruzs JM, Walker PD, Larsen CP: The histopathologic spectrum of kidney biopsies in patients with inflammatory bowel disease. Clin J Am Soc Nephrol 9: 265270, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 76.

    Izzedine H, Simon J, Piette AM, Lucsko M, Baumelou A, Charitanski D, et al.: Primary chronic interstitial nephritis in Crohn’s disease. Gastroenterology 123: 14361440, 2002 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 77.

    Tokuyama H, Wakino S, Konishi K, Hashiguchi A, Hayashi K, Itoh H: Acute interstitial nephritis associated with ulcerative colitis. Clin Exp Nephrol 14: 483486, 2010 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 78.

    Herrlinger KR, Noftz MK, Fellermann K, Schmidt K, Steinhoff J, Stange EF: Minimal renal dysfunction in inflammatory bowel disease is related to disease activity but not to 5-ASA use. Aliment Pharmacol Ther 15: 363369, 2001 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 79.

    Fraser JSMA, Muller AF, Smith DJ, Newman DJ, Lamb EJ: Renal tubular injury is present in acute inflammatory bowel disease prior to the introduction of drug therapy. Aliment Pharmacol Ther 15: 11311137, 2001 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 80.

    Johnson RJ, Bakris GL, Borghi C, Chonchol MB, Feldman D, Lanaspa MA, et al.: Hyperuricemia, acute and chronic kidney disease, hypertension, and cardiovascular disease: Report of a scientific workshop organized by the National Kidney Foundation. Am J Kidney Dis 71: 851865, 2018 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 81.

    Foley RJ, Weinman EJ: Urate nephropathy. Am J Med Sci 288: 208211, 1984 PubMed

  • 82.

    Krishnan E: Reduced glomerular function and prevalence of gout: NHANES 2009-10. PLoS One 7: e50046, 2012 PubMed

  • 83.

    Nakhoul GN, Huang H, Arrigain S, Jolly SE, Schold JD, Nally JV Jr, et al.: Serum potassium, end-stage renal disease and mortality in chronic kidney disease. Am J Nephrol 41: 456463, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 84.

    Yalamanchili HB, Calp-Inal S, Zhou XJ, Choudhury D: Hypokalemic nephropathy. Kidney Int Rep 3: 14821488, 2018 PubMed

  • 85.

    Fogo AB, Lusco MA, Najafian B, Alpers CE: AJKD atlas of renal pathology: nephrocalcinosis and acute phosphate nephropathy. Am J Kidney Dis 69: e17e18, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 86.

    Robijn S, Hoppe B, Vervaet BA, D’Haese PC, Verhulst A: Hyperoxaluria: A gut-kidney axis? Kidney Int 80: 11461158, 2011 PubMed

  • 87.

    Buysschaert B, Aydin S, Morelle J, Gillion V, Jadoul M, Demoulin N: Etiologies, clinical features, and outcome of oxalate nephropathy. Kidney Int Rep 5: 15031509, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 88.

    Yang Y, Sharma PD, Nair V, Jhaveri KD, Malieckal DA, Wanchoo R, et al.: Kidney oxalate crystal deposition in adult patients: A relatively common finding. Clin Nephrol 93: 243250, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 89.

    Salomon R, Saunier S, Niaudet P: Nephronophthisis. Pediatr Nephrol 24: 23332344, 2009 PubMed

  • 90.

    Eckardt KU, Alper SL, Antignac C, Bleyer AJ, Chauveau D, Dahan K, et al; Kidney Disease: Improving Global Outcomes: Autosomal dominant tubulointerstitial kidney disease: Diagnosis, classification, and management--A KDIGO consensus report. Kidney Int 88: 676683, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 91.

    Scolari F, Ghiggeri GM: Nephronophthisis-medullary cystic kidney disease: From bedside to bench and back again. Saudi J Kidney Dis Transpl 14: 316327, 2003 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 92.

    Landrigan PJ: Occupational and community exposures to toxic metals: Lead, cadmium, mercury and arsenic. West J Med 137: 531539, 1982 PubMed

  • 93.

    Brewster UC, Perazella MA: A review of chronic lead intoxication: An unrecognized cause of chronic kidney disease. Am J Med Sci 327: 341347, 2004 PubMed

  • 94.

    Nriagu JO: Saturnine gout among Roman aristocrats. Did lead poisoning contribute to the fall of the Empire? N Engl J Med 308: 660663, 1983 PubMed

  • 95.

    Moorthy S, Samuel AE, Moideen F, Peringat J: Interstitial nephritis presenting as acute kidney injury following ingestion of alternative medicine containing lead: A case report. Adv J Emerg Med 3: e8, 2018 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 96.

    Evans M, Elinder CG: Chronic renal failure from lead: myth or evidence-based fact? Kidney Int 79: 272279, 2011 PubMed

  • 97.

    Ordunez P, Nieto FJ, Martinez R, Soliz P, Giraldo GP, Mott SA, et al.: Chronic kidney disease mortality trends in selected Central America countries, 1997-2013: Clues to an epidemic of chronic interstitial nephritis of agricultural communities. J Epidemiol Community Health 72: 280286, 2018 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 98.

    Ordunez P, Martinez R, Reveiz L, Chapman E, Saenz C, Soares da Silva A, et al.: Chronic kidney disease epidemic in Central America: Urgent public health action is needed amid causal uncertainty. PLoS Negl Trop Dis 8: e3019, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 99.

    Floris M, Lepori N, Angioi A, Cabiddu G, Piras D, Loi V, et al.: Chronic kidney disease of undetermined etiology around the world. Kidney Blood Press Res 46: 142151, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 100.

    García-Trabanino R, Jarquín E, Wesseling C, Johnson RJ, González-Quiroz M, Weiss I, et al.: Heat stress, dehydration, and kidney function in sugarcane cutters in El Salvador—A cross-shift study of workers at risk of Mesoamerican nephropathy. Environ Res 142: 746755, 2015 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 101.

    Anupama YJ, Sankarasubbaiyan S, Taduri G: Chronic kidney disease of unknown etiology: Case definition for India—A perspective. Indian J Nephrol 30: 236240, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 102.

    Wijkström J, González-Quiroz M, Hernandez M, Trujillo Z, Hultenby K, Ring A, et al.: Renal morphology, clinical findings, and progression rate in mesoamerican nephropathy. Am J Kidney Dis 69: 626636, 2017 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 103.

    Wijkström J, Gonzalez-Quiroz M, Leiva R, Trujillo ZC, Elinder CG, Wernerson A: Mesoamerican nephropathy and kidney disease progression: A case series of individuals with kidney biopsies from Nicaragua and El Salvador. Kidney Med 3: 871873, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 104.

    Pavlović NM: Balkan endemic nephropathy-current status and future perspectives. Clin Kidney J 6: 257265, 2013 PubMed

  • 105.

    Stefanovic V, Radovanovic Z: Balkan endemic nephropathy and associated urothelial cancer. Nat Clin Pract Urol 5: 105112, 2008 PubMed

  • 106.

    Grollman AP, Shibutani S, Moriya M, Miller F, Wu L, Moll U, et al.: Aristolochic acid and the etiology of endemic (Balkan) nephropathy. Proc Natl Acad Sci U S A 104: 1212912134, 2007 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 107.

    Toncheva D, Dimitrov T, Stojanova S: Etiology of Balkan endemic nephropathy: A multifactorial disease? Eur J Epidemiol 14: 389394, 1998 PubMed

  • 108.

    Dittrich D, Maskalan M, Kastelan Z, Palenkic H, Grubic Z: The role of HLA in Balkan endemic nephropathy. Gene 767: 145179, 2021 PubMed

  • 109.

    Ferluga D, Hvala A, Vizjak A, Trnacević S, Halilbasić A: Renal function, protein excretion, and pathology of Balkan endemic nephropathy. III. Light and electron microscopic studies. Kidney Int Suppl 34: S57S67, 1991 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 110.

    Jelaković B, Nikolić J, Radovanović Z, Nortier J, Cosyns JP, Grollman AP, et al.: Consensus statement on screening, diagnosis, classification and treatment of endemic (Balkan) nephropathy. Nephrol Dial Transplant 29: 20202027, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 111.

    Klaus R, Niyazi M, Lange-Sperandio B: Radiation-induced kidney toxicity: molecular and cellular pathogenesis. Radiat Oncol 16: 43, 2021 PubMed

  • 112.

    Dong J, Li Y, Yue S, Liu X, Wang L, Xiong M, et al.: The profiles of biopsy-proven renal tubulointerstitial lesions in patients with glomerular disease. Ann Transl Med 8: 1066, 2020 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 113.

    Nakabayashi K, Sumiishi A, Sano K, Fujioka Y, Yamada A, Karube M, et al.: Tubulointerstitial nephritis without glomerular lesions in three patients with myeloperoxidase-ANCA-associated vasculitis. Clin Exp Nephrol 13: 605613, 2009 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 114.

    Plafkin C, Zhong W, Singh T: ANCA vasculitis presenting with acute interstitial nephritis without glomerular involvement. Clin Nephrol Case Stud 7: 4650, 2019 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 115.

    Martínez-Valenzuela L, Draibe J, Fulladosa X, Gomà M, Gómez F, Antón P, et al.: Acute tubulointerstitial nephritis in clinical oncology: A comprehensive review. Int J Mol Sci 22: 2326, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 116.

    Robles NR, Lopez-Gomez J, Garcia-Pino G, Ferreira F, Alvarado R, Sanchez-Casado E, et al.: Use of α1-microglobulin for diagnosing chronic interstitial nephropathy. Clin Exp Med 14: 315320, 2014 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 117.

    Stefanović V, Djukanović L, Cukuranović R, Bukvić D, Ležaić V, Marić I, et al.: Beta2-microglobulin and alpha1-microglobulin as markers of Balkan endemic nephropathy, a worldwide disease. Ren Fail 33: 176183, 2011 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 118.

    Moledina DG, Wilson FP, Kukova L, Obeid W, Luciano R, Kuperman M, et al.: Urine interleukin-9 and tumor necrosis factor-α for prognosis of human acute interstitial nephritis. Nephrol Dial Transplant 36: 18511858, 2021 PubMed

    • PubMed
    • Search Google Scholar
    • Export Citation

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