Characteristics of End-Stage Kidney Disease Patients
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  • 1 Division of Nephrology, Icahn School of Medicine at Mount Sinai; Brookdale Department of Geriatrics and Palliative Medicine
  • 1.

    United States Renal Data System: US Renal Data System 2019 Annual Data Report: Epidemiology of Kidney Disease in the United States. 2019. Available at: https://www.usrds.org/annual-data-report/. Accessed XXXXX.

    • Search Google Scholar
    • Export Citation
  • 2.

    Chen JC, Thorsteinsdottir B, Vaughan LE, Feely MA, Albright RC, Onuigbo M, et al.: End of life, withdrawal, and palliative care utilization among patients receiving maintenance hemodialysis therapy. Clin J Am Soc Nephrol 13: 11721179, 2018 10.2215/CJN.00590118PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 3.

    Wong SPY, Yu MK, Green PK, Liu CF, Hebert PL, O’Hare AM: End-of-life care for patients with advanced kidney disease in the US Veterans Affairs Health Care System, 2000–2011. Am J Kidney Dis 72: 4249, 2018 10.1053/j.ajkd.2017.11.007PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 4.

    Lin E, Bhattacharya J, Chertow GM: Prior hospitalization burden and the relatedness of 30-day readmissions in patients receiving hemodialysis. J Am Soc Nephrol 30: 323335, 2019 10.1681/ASN.2018080858PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 5.

    Plantinga LC, King L, Patzer RE, Lea JP, Burkart JM, Hockenberry JM, et al.: Early hospital readmission among hemodialysis patients in the United States is associated with subsequent mortality. Kidney Int 92: 934941, 2017 10.1016/j.kint.2017.03.025PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 6.

    Chan L, Chauhan K, Poojary P, Saha A, Hammer E, Vassalotti JA, et al.: National estimates of 30-day unplanned readmissions of patients on maintenance hemodialysis. Clin J Am Soc Nephrol 12: 16521662, 2017 10.2215/CJN.02600317PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7.

    Hickson LJ, Thorsteinsdottir B, Ramar P, Reinalda MS, Crowson CS, Williams AW, et al.: Hospital readmission among new dialysis patients associated with young age and poor functional status. Nephron 139: 112, 2018 10.1159/000485985PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 8.

    Plantinga LC, King LM, Masud T, Shafi T, Burkart JM, Lea JP, et al.: Burden and correlates of readmissions related to pulmonary edema in US hemodialysis patients: A cohort study. Nephrol Dial Transplant 33: 12151223, 2018 10.1093/ndt/gfx335PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 9.

    Wetmore JB, Molony JT, Liu J, Peng Y, Herzog CA, Collins AJ, et al.: Readmissions following a hospitalization for cardiovascular events in dialysis patients: A retrospective cohort study. J Am Heart Assoc 7: 2018 10.1161/JAHA.117.007231PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10.

    Plantinga LC, Masud T, Lea JP, Burkart JM, O’Donnell CM, Jaar BG: Post-hospitalization dialysis facility processes of care and hospital readmissions among hemodialysis patients: a retrospective cohort study. BMC Nephrol 19: 186, 2018 10.1186/s12882-018-0983-5PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 11.

    Sahlie A, Jaar BG, Paez LG, Masud T, Lea JP, Burkart JM, et al.: Burden and correlates of hospital readmissions among U.S. peritoneal dialysis patients. Perit Dial Int 39: 261267, 2019 10.3747/pdi.2018.00175PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 12.

    Ross KH, Jaar BG, Lea JP, Masud T, Patzer RE, Plantinga LC: Long-term outcomes among Medicare patients readmitted in the first year of hemodialysis: A retrospective cohort study. BMC Nephrol 20: 285, 2019 10.1186/s12882-019-1473-0PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 13.

    Neumann D, Mau W, Wienke A, Girndt M: Peritoneal dialysis is associated with better cognitive function than hemodialysis over a one-year course. Kidney Int 93: 430438, 2018 10.1016/j.kint.2017.07.022PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 14.

    Ali H, Soliman K, Mohamed MM, Daoud A, Shafiq T, Fulop T, et al.: The effects of dialysis modality choice on cognitive functions in patients with end-stage renal failure: A systematic review and meta-analysis. Int Urol Nephrol 53: 155163, 2021 10.1007/s11255-020-02603-xPubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 15.

    Tian X, Guo X, Xia X, Yu H, Li X, Jiang A: The comparison of cognitive function and risk of dementia in CKD patients under peritoneal dialysis and hemodialysis: A PRISMA-compliant systematic review and meta-analysis. Medicine (Baltimore) 98: e14390, 2019 10.1097/MD.0000000000014390PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 16.

    van Deudekom FJ, Kallenberg MH, Berkhout-Byrne NC, Blauw GJ, Boom H, de Bresser J, et al.: Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study. BMC Nephrol 21: 126, 2020 10.1186/s12882-020-01764-2PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 17.

    Zhang YH, Yang ZK, Wang JW, Xiong ZY, Liao JL, Hao L, et al.: Cognitive changes in peritoneal dialysis patients: A multicenter prospective cohort study. Am J Kidney Dis 72: 691700, 2018 10.1053/j.ajkd.2018.04.020PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 18.

    Wolfgram DF: Intradialytic cerebral hypoperfusion as mechanism for cognitive impairment in patients on hemodialysis. J Am Soc Nephrol 30: 20522058, 2019 10.1681/ASN.2019050461PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 19.

    Johansen KL, Delgado C, Kaysen GA, Chertow GM, Chiang J, Dalrymple LS, et al.: Frailty among patients receiving hemodialysis: Evolution of components and associations with mortality. J Gerontol A Biol Sci Med Sci 74: 380386, 2019 10.1093/gerona/gly206PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 20.

    Chu NM, Chen X, Norman SP, Fitzpatrick J, Sozio SM, Jaar BG, et al. Frailty prevalence in younger end-stage kidney disease patients undergoing dialysis and transplantation. Am J Nephrol 51: 501510, 2020. PubMed

    • Search Google Scholar
    • Export Citation
  • 21.

    Goto NA, van Loon IN, Morpey MI, Verhaar MC, Willems HC, Emmelot-Vonk MH, et al.: Geriatric assessment in elderly patients with end-stage kidney disease. Nephron 141: 4148, 2019 10.1159/000494222PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 22.

    van Loon IN, Goto NA, Boereboom FTJ, Bots ML, Verhaar MC, Hamaker ME: Frailty screening tools for elderly patients incident to dialysis. Clin J Am Soc Nephrol 12: 14801488, 2017 10.2215/CJN.11801116PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 23.

    Garcia-Canton C, Rodenas A, Lopez-Aperador C, Rivero Y, Anton G, Monzon T, et al.: Frailty in hemodialysis and prediction of poor short-term outcome: Mortality, hospitalization and visits to hospital emergency services. Ren Fail 41: 567575, 2019 10.1080/0886022X.2019.1628061PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 24.

    van Loon IN, Goto NA, Boereboom FTJ, Bots ML, Hoogeveen EK, Gamadia L, et al.: Geriatric assessment and the relation with mortality and hospitalizations in older patients starting dialysis. Nephron 143: 108119, 2019 10.1159/000501277PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 25.

    Brar R, Whitlock R, Komenda P, Lerner B, Prasad B, Bohm C, et al.: The impact of frailty on technique failure and mortality in patients on home dialysis. Perit Dial Int 39: 532538, 2019 10.3747/pdi.2018.00195PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 26.

    Haugen CE, Chu NM, Ying H, Warsame F, Holscher CM, Desai NM, et al.: Frailty and access to kidney transplantation. Clin J Am Soc Nephrol 14: 576582, 2019 10.2215/CJN.12921118PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 27.

    Zhang Q, Ma Y, Lin F, Zhao J, Xiong J: Frailty and mortality among patients with chronic kidney disease and end-stage renal disease: A systematic review and meta-analysis. Int Urol Nephrol 52: 363370, 2020 10.1007/s11255-019-02369-xPubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 28.

    Kuki A, Tanaka K, Kushiyama A, Tanaka Y, Motonishi S, Sugano Y, et al.: Association of gait speed and grip strength with risk of cardiovascular events in patients on haemodialysis: A prospective study. BMC Nephrol 20: 196, 2019 10.1186/s12882-019-1370-6PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 29.

    Brown EA, Farrington K: Geriatric assessment in advanced kidney disease. Clin J Am Soc Nephrol 14: 10911093, 2019 10.2215/CJN.14771218PubMed

  • 30.

    Ishida JH, McCulloch CE, Steinman MA, Grimes BA, Johansen KL: Opioid analgesics and adverse outcomes among hemodialysis patients. Clin J Am Soc Nephrol 13: 746753, 2018 10.2215/CJN.09910917PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 31.

    Kimmel PL, Fwu CW, Abbott KC, Eggers AW, Kline PP, Eggers PW: Opioid prescription, morbidity, and mortality in United States dialysis patients. J Am Soc Nephrol 28: 36583670, 2017 10.1681/ASN.2017010098PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 32.

    Ishida JH, McCulloch CE, Steinman MA, Grimes BA, Johansen KL: Gabapentin and pregabalin use and association with adverse outcomes among hemodialysis patients. J Am Soc Nephrol 29: 19701978, 2018 10.1681/ASN.2018010096PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 33.

    Lai KM, Chen TL, Chang CC, Chen HH, Lee YW: Association between NSAID use and mortality risk in patients with end-stage renal disease: A population-based cohort study. Clin Epidemiol 11: 429441, 2019 10.2147/CLEP.S204322PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 34.

    Liao YC, Chang CC, Chen TL, Liu CC, Chen HH, Lee YW: Association between nonsteroidal anti-inflammatory drug use and major adverse cardiovascular events in patients with end-stage renal disease: A population-based cohort study. J Nephrol ▪▪▪: 2020 10.1007/s40620-020-00830-0PubMed

    • Search Google Scholar
    • Export Citation
  • 35.

    Chauvin KJ, Blake PG, Garg AX, Weir MA, Bathini L, Dixon SN, et al.: Baclofen has a risk of encephalopathy in older adults receiving dialysis. Kidney Int 98: 979988, 2020 10.1016/j.kint.2020.04.047PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 36.

    Rhee EP, Guallar E, Hwang S, Kim N, Tonelli M, Moe SM, et al.: Prevalence and persistence of uremic symptoms in incident dialysis patients. Kidney360 1: 8692, 2020 10.34067/KID.0000072019PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 37.

    Simonsen E, Komenda P, Lerner B, Askin N, Bohm C, Shaw J, et al.: Treatment of uremic pruritus: A systematic review. Am J Kidney Dis 70: 638655, 2017 10.1053/j.ajkd.2017.05.018PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 38.

    Fishbane S, Jamal A, Munera C, Wen W, Menzaghi F; KALM-1 Trial Investigators: A Phase 3 trial of difelikefalin in hemodialysis patients with pruritus. N Engl J Med 382: 222232, 2020 10.1056/NEJMoa1912770PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 39.

    Ladin K, Pandya R, Kannam A, Loke R, Oskoui T, Perrone RD, et al.: Discussing conservative management with older patients with CKD: An interview study of nephrologists. Am J Kidney Dis 71: 627635, 2018 10.1053/j.ajkd.2017.11.011PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 40.

    Ladin K, Pandya R, Perrone RD, Meyer KB, Kannam A, Loke R, et al.: Characterizing approaches to dialysis decision making with older adults: A qualitative study of nephrologists. Clin J Am Soc Nephrol 13: 11881196, 2018 10.2215/CJN.01740218PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 41.

    Wong SPY, McFarland LV, Liu CF, Laundry RJ, Hebert PL, O’Hare AM: Care practices for patients with advanced kidney disease who forgo maintenance dialysis. JAMA Intern Med 179: 305313, 2019 10.1001/jamainternmed.2018.6197PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 42.

    Wong SPY, Boyapati S, Engelberg RA, Thorsteinsdottir B, Taylor JS, O’Hare AM: Experiences of US nephrologists in the delivery of conservative care to patients with advanced kidney disease: A national qualitative study. Am J Kidney Dis 75: 167176, 2020 10.1053/j.ajkd.2019.07.006PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 43.

    Harrison TG, Tam-Tham H, Hemmelgarn BR, James MT, Sinnarajah A, Thomas CM: Identification and prioritization of quality indicators for conservative kidney management. Am J Kidney Dis 73: 174183, 2019 10.1053/j.ajkd.2018.08.014PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 44.

    van Loon IN, Goto NA, Boereboom FTJ, Verhaar MC, Bots ML, Hamaker ME: Quality of life after the initiation of dialysis or maximal conservative management in elderly patients: a longitudinal analysis of the Geriatric assessment in OLder patients starting Dialysis (GOLD) study. BMC Nephrol 20: 108, 2019 10.1186/s12882-019-1268-3PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 45.

    Tam-Tham H, Quinn RR, Weaver RG, Zhang J, Ravani P, Liu P, et al.: Survival among older adults with kidney failure is better in the first three years with chronic dialysis treatment than not. Kidney Int 94: 582588, 2018 10.1016/j.kint.2018.03.007PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 46.

    Verberne WR, Dijkers J, Kelder JC, Geers ABM, Jellema WT, Vincent HH, et al.: Value-based evaluation of dialysis versus conservative care in older patients with advanced chronic kidney disease: A cohort study. BMC Nephrol 19: 205, 2018 10.1186/s12882-018-1004-4PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 47.

    Kurella Tamura M, Desai M, Kapphahn KI, Thomas IC, Asch SM, Chertow GM: Dialysis versus medical management at different ages and levels of kidney function in veterans with advanced CKD. J Am Soc Nephrol 29: 21692177, 2018 10.1681/ASN.2017121273PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 48.

    Shah KK, Murtagh FEM, McGeechan K, Crail SM, Burns A, Morton RL: Quality of life among caregivers of people with end-stage kidney disease managed with dialysis or comprehensive conservative care. BMC Nephrol 21: 160, 2020 10.1186/s12882-020-01830-9PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 49.

    Sellars M, Clayton JM, Morton RL, Luckett T, Silvester W, Spencer L, et al.: An interview study of patient and caregiver perspectives on advance care planning in ESRD. Am J Kidney Dis 71: 216224, 2018 10.1053/j.ajkd.2017.07.021PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 50.

    Bradshaw CL, Gale RC, Chettiar A, Ghaus SJ, Thomas IC, Fung E, et al.: Medical record documentation of goals-of-care discussions among older veterans with incident kidney failure. Am J Kidney Dis 75: 744752, 2020 10.1053/j.ajkd.2019.07.024PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 51.

    Chan L, Jaladanki SK, Somani S, Paranjpe I, Kumar A, Zhao S, et al. Mount Sinai COVID Informatics Center (MSCIC): Outcomes of patients on maintenance dialysis hospitalized with COVID-19. Clin J Am Soc Nephrol ▪▪▪: CJN.12360720, 2020 10.2215/CJN.12360720PubMed

    • Search Google Scholar
    • Export Citation
  • 52.

    Valeri AM, Robbins-Juarez SY, Stevens JS, Ahn W, Rao MK, Radhakrishnan J, et al.: Presentation and Outcomes of Patients with ESKD and COVID-19. J Am Soc Nephrol 31: 14091415, 2020 10.1681/ASN.2020040470PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 53.

    Weiss S, Bhat P, Del Pilar Fernandez M, Bhat JG, Coritsidis GN: COVID-19 infection in ESKD: Findings from a prospective disease surveillance program at dialysis facilities in New York City and Long Island. J Am Soc Nephrol 31: 25172521, 2020 10.1681/ASN.2020070932PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 54.

    Clarke C, Prendecki M, Dhutia A, Ali MA, Sajjad H, Shivakumar O, et al.: High prevalence of asymptomatic COVID-19 infection in hemodialysis patients detected using serologic screening. J Am Soc Nephrol 31: 19691975, 2020 10.1681/ASN.2020060827PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 55.

    Shaikh A, Zeldis E, Campbell KN, Chan L: Prolonged SARS-CoV-2 viral RNA shedding and IgG antibody response to SARS-CoV-2 in patients on hemodialysis. Clin J Am Soc Nephrol 16: 290292, 2021 10.2215/CJN.11120720PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 56.

    Yau K, Muller MP, Lin M, Siddiqui N, Neskovic S, Shokar G, et al.: COVID-19 outbreak in an urban hemodialysis unit. Am J Kidney Dis 76: 690695 e1, 2020 10.1053/j.ajkd.2020.07.001PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 57.

    Ng JH, Hirsch JS, Wanchoo R, Sachdeva M, Sakhiya V, Hong S, et al., Northwell COVID-19 Research Consortium and the Northwell Nephrology COVID-19 Research Consortium: Outcomes of patients with end-stage kidney disease hospitalized with COVID-19. Kidney Int 98: 15301539, 2020 10.1016/j.kint.2020.07.030PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 58.

    Jiang HJ, Tang H, Xiong F, Chen WL, Tian JB, Sun J, et al.: COVID-19 in peritoneal dialysis patients. Clin J Am Soc Nephrol 16: 121123, 2020 10.2215/CJN.07200520PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 59.

    Sachdeva M, Uppal NN, Hirsch JS, Ng JH, Malieckal D, Fishbane S, et al.: COVID-19 in hospitalized patients on chronic peritoneal dialysis: A case series. Am J Nephrol 51: 669674, 2020 10.1159/000510259PubMed

    • Crossref
    • Search Google Scholar
    • Export Citation

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