Primary Nephrotic Syndrome
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Landan Zand Division of Nephrology and Hypertension, University of Minnesota, Minneapolis, Minnesota

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Fernando C. Fervenza Department of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota

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  • 1.

    Glassock RJ , Fervenza FC , Hebert L , Cameron JS : Nephrotic syndrome redux. Nephrol Dial Transplant 30: 1217, 2015 PubMed

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    Meyrier A , Niaudet P : Acute kidney injury complicating nephrotic syndrome of minimal change disease. Kidney Int 94: 861869, 2018 PubMed

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    Glassock RJ : Secondary minimal change disease. Nephrol Dial Transplant 18[Suppl 6]: vi52vi58, 2003 PubMed

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    Clement LC , Macé C , Avila-Casado C , Joles JA , Kersten S , Chugh SS : Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome. Nat Med 20: 3746, 2014 PubMed

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    Boumediene A , Vachin P , Sendeyo K , Oniszczuk J , Zhang SY , Henique C , et al.: NEPHRUTIX: A randomized, double-blind, placebo vs rituximab-controlled trial assessing T-cell subset changes in minimal change nephrotic syndrome. J Autoimmun 88: 91102, 2018 PubMed

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    Webb NJA , Woolley RL , Lambe T , Frew E , Brettell EA , Barsoum EN , et al.; PREDNOS Collaborative Group: Long term tapering versus standard prednisolone treatment for first episode of childhood nephrotic syndrome: Phase III randomised controlled trial and economic evaluation. BMJ 365: l1800, 2019 PubMed

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    Hahn D , Hodson EM , Willis NS , Craig JC : Corticosteroid therapy for nephrotic syndrome in children. Cochrane Database Syst Rev CD001533: CD001533, 2015 PubMed

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    Li H , Shi X , Shen H , Li X , Wang H , Li H , et al.: Tacrolimus versus intravenous pulse cyclophosphamide therapy in Chinese adults with steroid-resistant idiopathic minimal change nephropathy: A multicenter, open-label, nonrandomized cohort trial. Clin Ther 34: 11121120, 2012 PubMed

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    Li X , Li H , Chen J , He Q , Lv R , Lin W , et al.: Tacrolimus as a steroid-sparing agent for adults with steroid-dependent minimal change nephrotic syndrome. Nephrol Dial Transplant 23: 19191925, 2008 PubMed

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    Meyrier A , Condamin MC , Broneer D ; Collaborative Group of the French Society of Nephrology: Treatment of adult idiopathic nephrotic syndrome with cyclosporin A: Minimal-change disease and focal-segmental glomerulosclerosis. Clin Nephrol 35[Suppl 1]: S37S42, 1991 PubMed

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    Li X , Liu Z , Wang L , Wang R , Ding G , Shi W , et al.: Tacrolimus monotherapy after intravenous methylprednisolone in adults with minimal change nephrotic syndrome. J Am Soc Nephrol 28: 12861295, 2017 PubMed

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    Medjeral-Thomas NR , Lawrence C , Condon M , Sood B , Warwicker P , Brown H , et al.: Randomized, controlled trial of tacrolimus and prednisolone monotherapy for adults with de novo minimal change disease: A multicenter, randomized, controlled trial. Clin J Am Soc Nephrol 15: 209218, 2020 PubMed

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    Gellermann J , Weber L , Pape L , Tönshoff B , Hoyer P , Querfeld U ; Gesellschaft für Pädiatrische Nephrologie (GPN): Mycophenolate mofetil versus cyclosporin A in children with frequently relapsing nephrotic syndrome. J Am Soc Nephrol 24: 16891697, 2013 PubMed

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    Geng HY , Ji LN , Chen CY , Tu J , Li HR , Bao R , et al.: [Mycophenolate mofetil versus cyclosporine A in children with primary refractory nephrotic syndrome]. Zhonghua Er Ke Za Zhi 56: 651656, 2018 PubMed

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    Sinha A , Puraswani M , Kalaivani M , Goyal P , Hari P , Bagga A : Efficacy and safety of mycophenolate mofetil versus levamisole in frequently relapsing nephrotic syndrome: An open-label randomized controlled trial. Kidney Int 95: 210218, 2019 PubMed

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    Iijima K , Sako M , Nozu K , Mori R , Tuchida N , Kamei K , et al.; Rituximab for Childhood-onset Refractory Nephrotic Syndrome (RCRNS) Study Group: Rituximab for childhood-onset, complicated, frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicentre, double-blind, randomised, placebo-controlled trial. Lancet 384: 12731281, 2014 PubMed

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    Ravani P , Rossi R , Bonanni A , Quinn RR , Sica F , Bodria M , et al.: Rituximab in children with steroid-dependent nephrotic syndrome: A multicenter, open-label, noninferiority, randomized controlled trial. J Am Soc Nephrol 26: 22592266, 2015 PubMed

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    Ruggenenti P , Ruggiero B , Cravedi P , Vivarelli M , Massella L , Marasà M , et al.; Rituximab in Nephrotic Syndrome of Steroid-Dependent or Frequently Relapsing Minimal Change Disease Or Focal Segmental Glomerulosclerosis (NEMO) Study Group: Rituximab in steroid-dependent or frequently relapsing idiopathic nephrotic syndrome. J Am Soc Nephrol 25: 850863, 2014 PubMed

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    Hogan J , Dossier C , Kwon T , Macher MA , Maisin A , Couderc A , et al.: Effect of different rituximab regimens on B cell depletion and time to relapse in children with steroid-dependent nephrotic syndrome. Pediatr Nephrol 34: 253259, 2019 PubMed

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    Fenoglio R , Sciascia S , Beltrame G , Mesiano P , Ferro M , Quattrocchio G , et al.: Rituximab as a front-line therapy for adult-onset minimal change disease with nephrotic syndrome. Oncotarget 9: 2879928804, 2018 PubMed

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