Entering the Golden Age
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  • 1 Faculty of Medicine, University of Toronto, Toronto, Ontario, CanadaToronto General Research Institute, Toronto, Ontario, Canada
  • 1.

    Xie J, Liu L, Mladkova N, Li Y, Ren H, Wang W, : The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis. Nat Commun 11: 1600, 2020 10.1038/s41467-020-15383-w PubMed

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  • 2.

    Yin L, Du G, Zhang B, Zhang H, Yin R, Zhang W, : Efficient drug screening and nephrotoxicity assessment on co-culture microfluidic kidney chip. Sci Rep 10: 6568, 2020 10.1038/s41598-020-63096-3 PubMed

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  • 3.

    Feng D, Kumar M, Muntel J, Gurley SB, Birrane G, Stillman IE, : Phosphorylation of ACTN4 leads to podocyte vulnerability and proteinuric glomerulosclerosis. J Am Soc Nephrol 31: 14791495, 2020 10.1681/ASN.2019101032 PubMed

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  • 4.

    Barbour SJ, Coppo R, Zhang H, Liu ZH, Suzuki Y, Matsuzaki K, ; International IgA Nephropathy Network: Evaluating a new international risk-prediction tool in IgA nephropathy. JAMA Intern Med 179: 942952, 2019 10.1001/jamainternmed.2019.0600 PubMed

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  • 5.

    Barbour SJ, Canney M, Coppo R, Zhang H, Liu ZH, Suzuki Y, ; International IgA Nephropathy Network: Improving treatment decisions using personalized risk assessment from the International IgA Nephropathy Prediction Tool. Kidney Int: S0085-2538(20)30544-5, 2020 PubMed

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  • 6.

    Leaf DE, Appel GB, Radhakrishnan J: Glomerular disease: Why is there a dearth of high quality clinical trials? Kidney Int 78: 337342, 2010 10.1038/ki.2010.156 PubMed

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    https://rarediseases.info.nih.gov/diseases/pages/31/faqs-about-rare-diseases#. Accessed August 20, 2020

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    https://ncats.nih.gov/engagement/rare-diseases-community-resources. Accessed August 21, 2020

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    Gadegbeku CA, Gipson DS, Holzman LB, Ojo AO, Song PX, Barisoni L, : Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach. Kidney Int 83: 749756, 2013 10.1038/ki.2012.428 PubMed

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  • 10.

    Krischer JP, Gopal-Srivastava R, Groft SC, Eckstein DJ; Rare Diseases Clinical Research Network: The Rare Diseases Clinical Research Network’s organization and approach to observational research and health outcomes research. J Gen Intern Med 29[Suppl 111]: S739S744, 2014 10.1007/s11606-014-2894-x PubMed

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  • 11.

    Barra L, Borchin RL, Burroughs C, Casey GC, McAlear CA, Sreih AG: Impact of vasculitis on employment and income. Vasculitis Clinical Research Consortium and the Vasculitis Patient-Powered Research Network. 36. Clin Exp Rheumatol 36[Suppl 3]: 5864, 2018 Epub 2018 Jan 10.

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  • 12.

    Thompson A, Cattran DC, Blank M, Nachman PH: Complete and partial remission as surrogate end points in membranous Nephropathy. J Am Soc Nephrol 26: 29302937, 2015 10.1681/ASN.2015010091 PubMed

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  • 13.

    Rauen T, Eitner F, Fitzner C, Sommerer C, Zeier M, Otte B, ; STOP-IgAN Investigators: Intensive supportive care plus immunosuppression in IgA nephropathy. N Engl J Med 373: 22252236, 2015 10.1056/NEJMoa1415463 PubMed

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  • 14.

    Lv J, Zhang H, Wong MG, Jardine MJ, Hladunewich M, Jha V, ; TESTING Study Group: Effect of oral methylprednisolone on clinical outcomes in patients with IgA nephropathy: The TESTING randomized clinical trial. JAMA 318: 432442, 2017 10.1001/jama.2017.9362 PubMed

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  • 15.

    Thompson A, Carroll K, A Inker L, Floege J, Perkovic V, Boyer-Suavet S, : Proteinuria reduction as a surrogate end point in trials of IgA nephropathy. Clin J Am Soc Nephrol 14: 469481, 2019 10.2215/CJN.08600718 PubMed

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  • 16.

    Carter SA, Lightstone L, Cattran D, Bagga A, Barbour SJ, Barratt J, ; SONG-GD Initiative: Standardized Outcomes in Nephrology-Glomerular Disease (SONG-GD): establishing a core outcome set for trials in patients with glomerular disease. Kidney Int 95: 12801283, 2019 10.1016/j.kint.2019.01.047 PubMed

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  • 17.

    Carter SA, Gutman T, Logeman C, Cattran D, Lightstone L, Bagga A, ; SONG-GD Investigators: Identifying outcomes important to patients with glomerular disease and their caregivers. Clin J Am Soc Nephrol 15: 673684, 2020 10.2215/CJN.13101019 PubMed

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  • 18.

    Saran R, Robinson B, Abbott KC, Lawrence YC, Bragg-Gresham J, Balkrishnan R, .; US Renal Data System 2019 Annual Data Report: Epidemiology of kidney disease in the United States. Am J Kidney Dis 36[3 Suppl 1]: A7A8, 2019 10.1053/j.ajkd.2019.09.00

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  • 19.

    United States Renal Data System: 2019 USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States, Bethesda, MD, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2019

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  • 20.

    Canney M, Induruwage D, Sahota A, McCrory C, Hladunewich MA, Gill J, : Socioeconomic position and incidence of glomerular diseases. Clin J Am Soc Nephrol 15: 367374, 2020 10.2215/CJN.08060719 PubMed

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  • 21.

    Jafari H, Ebrahimi A, Aghaei A, Khatony A: The relationship between care burden and quality of life in caregivers of hemodialysis patients. BMC Nephrol 19: 321, 2018 10.1186/s12882-018-1120-1 PubMed

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  • 22.

    Wetmore JB, Guo H, Liu J, Collins AJ, Gilbertson DT: The incidence, prevalence, and outcomes of glomerulonephritis derived from a large retrospective analysis. Kidney Int 90: 853860, 2016 10.1016/j.kint.2016.04.026 PubMed

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  • 23.

    Cunningham A, Benediktsson H, Muruve DA, Hildebrand AM, Ravani P: Trends in biopsy-based diagnosis of kidney disease: a population study. Can J Kidney Health Dis 5: 2054358118799690, 2018 10.1177/2054358118799690 PubMed

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  • 24.

    Renal Data System: 2017 USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States, Bethesda, MD, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2019

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  • 25.

    Splinter A, Tjaden LA, Haverman L, Adams B, Collard L, Cransberg K, : Children on dialysis as well as renal transplanted children report severely impaired health-related quality of life. Qual Life Res 27: 14451454, 2018 10.1007/s11136-018-1789-4 PubMed

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  • 26.

    Barbour S, Lo C, Espino-Hernandez G, Gill J, Levin A: The BC Glomerulonephritis Network: improving access and reducing the cost of immunosuppressive treatments for glomerular diseases. Can J Kidney Health Dis 5: 2054358118759551, 2018 10.1177/2054358118759551 PubMed

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  • 27.

    Canney M, Induruwage D, McCandless LC, Reich HN, Barbour SJ: Disease-specific incident glomerulonephritis displays geographic clustering in under-serviced rural areas of British Columbia, Canada. Kidney Int 96: 421428, 2019 10.1016/j.kint.2019.02.032 PubMed

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